Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 11 studies | 46% ± 23% | |
| retina horizontal cell | 6 studies | 69% ± 9% | |
| interneuron | 5 studies | 46% ± 12% | |
| GABAergic neuron | 5 studies | 52% ± 13% | |
| neuron | 3 studies | 23% ± 7% | |
| amacrine cell | 3 studies | 44% ± 22% | |
| glycinergic amacrine cell | 3 studies | 32% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 8 studies | 37% ± 24% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 69% | 2639.87 | 1833 / 2642 | 73% | 17.62 | 512 / 705 |
| adrenal gland | 1% | 5.33 | 3 / 258 | 47% | 9.20 | 107 / 230 |
| lymph node | 0% | 0 | 0 / 0 | 31% | 2.25 | 9 / 29 |
| eye | 0% | 0 | 0 / 0 | 8% | 0.78 | 6 / 80 |
| pancreas | 0% | 0 | 0 / 328 | 1% | 0.02 | 2 / 178 |
| stomach | 0% | 0 | 0 / 359 | 1% | 0.17 | 2 / 286 |
| esophagus | 0% | 0 | 0 / 1445 | 1% | 0.01 | 1 / 183 |
| lung | 0% | 0 | 0 / 578 | 0% | 0.01 | 5 / 1155 |
| bladder | 0% | 0 | 0 / 21 | 0% | 0.02 | 2 / 504 |
| intestine | 0% | 0 | 0 / 966 | 0% | 0.01 | 2 / 527 |
| liver | 0% | 0 | 0 / 226 | 0% | 0.01 | 1 / 406 |
| prostate | 0% | 0 | 0 / 245 | 0% | 0.02 | 1 / 502 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0.02 | 1 / 901 |
| breast | 0% | 0 | 0 / 459 | 0% | 0.00 | 1 / 1118 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0 | 0 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ovary | 0% | 0 | 0 / 180 | 0% | 0 | 0 / 430 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| skin | 0% | 0 | 0 / 1809 | 0% | 0 | 0 / 472 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| thymus | 0% | 0 | 0 / 653 | 0% | 0 | 0 / 605 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| uterus | 0% | 0 | 0 / 170 | 0% | 0 | 0 / 459 |
| GO_0006605 | Biological process | protein targeting |
| GO_0098970 | Biological process | postsynaptic neurotransmitter receptor diffusion trapping |
| GO_0099590 | Biological process | neurotransmitter receptor internalization |
| GO_2000311 | Biological process | regulation of AMPA receptor activity |
| GO_0098943 | Biological process | neurotransmitter receptor transport, postsynaptic endosome to lysosome |
| GO_0051968 | Biological process | positive regulation of synaptic transmission, glutamatergic |
| GO_0008104 | Biological process | protein localization |
| GO_0019226 | Biological process | transmission of nerve impulse |
| GO_0099645 | Biological process | neurotransmitter receptor localization to postsynaptic specialization membrane |
| GO_0006816 | Biological process | calcium ion transport |
| GO_0070588 | Biological process | calcium ion transmembrane transport |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0098839 | Cellular component | postsynaptic density membrane |
| GO_0098685 | Cellular component | Schaffer collateral - CA1 synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030666 | Cellular component | endocytic vesicle membrane |
| GO_0036477 | Cellular component | somatodendritic compartment |
| GO_0032281 | Cellular component | AMPA glutamate receptor complex |
| GO_0030425 | Cellular component | dendrite |
| GO_0005891 | Cellular component | voltage-gated calcium channel complex |
| GO_0060076 | Cellular component | excitatory synapse |
| GO_0030165 | Molecular function | PDZ domain binding |
| GO_0005245 | Molecular function | voltage-gated calcium channel activity |
| GO_0016247 | Molecular function | channel regulator activity |
| GO_0035255 | Molecular function | ionotropic glutamate receptor binding |
| Gene name | CACNG3 |
| Protein name | Voltage-dependent calcium channel gamma-3 subunit (Neuronal voltage-gated calcium channel gamma-3 subunit) (Transmembrane AMPAR regulatory protein gamma-3) (TARP gamma-3) |
| Synonyms | |
| Description | FUNCTION: Regulates the trafficking to the somatodendritic compartment and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. . |
| Accessions | O60359 ENST00000005284.4 |
