AP3D1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0035646Biological processendosome to melanosome transport
GO_0036465Biological processsynaptic vesicle recycling
GO_0051138Biological processpositive regulation of NK T cell differentiation
GO_0016182Biological processsynaptic vesicle budding from endosome
GO_0006623Biological processprotein targeting to vacuole
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0046907Biological processintracellular transport
GO_0035654Biological processclathrin-coated vesicle cargo loading, AP-3-mediated
GO_0008089Biological processanterograde axonal transport
GO_0048499Biological processsynaptic vesicle membrane organization
GO_0006886Biological processintracellular protein transport
GO_0032438Biological processmelanosome organization
GO_0048490Biological processanterograde synaptic vesicle transport
GO_0016192Biological processvesicle-mediated transport
GO_0060155Biological processplatelet dense granule organization
GO_0098943Biological processneurotransmitter receptor transport, postsynaptic endosome to lysosome
GO_0006896Biological processGolgi to vacuole transport
GO_0140916Biological processzinc ion import into lysosome
GO_0072657Biological processprotein localization to membrane
GO_1903232Biological processmelanosome assembly
GO_0016183Biological processsynaptic vesicle coating
GO_0048007Biological processantigen processing and presentation, exogenous lipid antigen via MHC class Ib
GO_0098978Cellular componentglutamatergic synapse
GO_0016020Cellular componentmembrane
GO_0005769Cellular componentearly endosome
GO_0043195Cellular componentterminal bouton
GO_0098794Cellular componentpostsynapse
GO_0005794Cellular componentGolgi apparatus
GO_0030123Cellular componentAP-3 adaptor complex
GO_0000139Cellular componentGolgi membrane
GO_0098830Cellular componentpresynaptic endosome
GO_0010008Cellular componentendosome membrane
GO_1904115Cellular componentaxon cytoplasm
GO_0005765Cellular componentlysosomal membrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameAP3D1
Protein nameAdaptor related protein complex 3 subunit delta 1
AP3D1 protein
AP-3 complex subunit delta
AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adaptor-related protein complex 3 subunit delta-1) (Delta-adaptin)
SynonymsPRO0039
DescriptionFUNCTION: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation . In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity). .

FUNCTION: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. .

AccessionsK7ERW8
K7ELX8
ENST00000345016.9 [O14617-1]
ENST00000586370.6
ENST00000643010.1
Q6PK82
A0A2R8YCY8
ENST00000590683.2
A0A2R8Y4J3
A0A8V8TQW4
ENST00000643116.3 [O14617-5]
ENST00000591284.2
ENST00000589369.2
O14617
A0A087WYN6
ENST00000700387.1