Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte precursor cell | 14 studies | 52% ± 19% | |
| glutamatergic neuron | 13 studies | 76% ± 22% | |
| GABAergic neuron | 11 studies | 69% ± 24% | |
| oligodendrocyte | 10 studies | 28% ± 18% | |
| microglial cell | 8 studies | 37% ± 17% | |
| interneuron | 6 studies | 78% ± 15% | |
| neuron | 5 studies | 59% ± 21% | |
| endothelial cell | 5 studies | 40% ± 20% | |
| astrocyte | 5 studies | 37% ± 22% | |
| granule cell | 4 studies | 62% ± 21% | |
| amacrine cell | 4 studies | 53% ± 18% | |
| retina horizontal cell | 4 studies | 42% ± 28% | |
| retinal cone cell | 4 studies | 62% ± 18% | |
| retinal ganglion cell | 4 studies | 79% ± 17% | |
| retinal rod cell | 4 studies | 44% ± 11% | |
| GABAergic interneuron | 3 studies | 79% ± 2% | |
| GABAergic amacrine cell | 3 studies | 64% ± 17% | |
| OFF-bipolar cell | 3 studies | 49% ± 9% | |
| ON-bipolar cell | 3 studies | 49% ± 17% | |
| glycinergic amacrine cell | 3 studies | 53% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 98% | 1162.03 | 2580 / 2642 | 93% | 5.65 | 659 / 705 |
| ovary | 82% | 293.68 | 148 / 180 | 9% | 0.13 | 38 / 430 |
| prostate | 64% | 120.69 | 157 / 245 | 11% | 0.16 | 55 / 502 |
| pancreas | 58% | 90.34 | 191 / 328 | 4% | 0.13 | 7 / 178 |
| kidney | 42% | 54.98 | 37 / 89 | 17% | 0.31 | 150 / 901 |
| adrenal gland | 21% | 25.29 | 53 / 258 | 36% | 0.77 | 83 / 230 |
| heart | 44% | 80.11 | 378 / 861 | 0% | 0 | 0 / 0 |
| thymus | 42% | 46.93 | 276 / 653 | 1% | 0.02 | 7 / 605 |
| lung | 8% | 8.82 | 46 / 578 | 21% | 0.49 | 244 / 1155 |
| esophagus | 10% | 10.66 | 138 / 1445 | 16% | 0.31 | 30 / 183 |
| tonsil | 0% | 0 | 0 / 0 | 22% | 0.45 | 10 / 45 |
| uterus | 2% | 2.11 | 3 / 170 | 15% | 0.33 | 67 / 459 |
| intestine | 11% | 13.13 | 107 / 966 | 2% | 0.03 | 11 / 527 |
| breast | 9% | 10.23 | 41 / 459 | 4% | 0.08 | 44 / 1118 |
| bladder | 0% | 0 | 0 / 21 | 9% | 0.17 | 44 / 504 |
| stomach | 3% | 3.24 | 10 / 359 | 4% | 0.07 | 12 / 286 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.11 | 2 / 29 |
| adipose | 4% | 4.51 | 51 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 4% | 6.10 | 52 / 1335 | 0% | 0 | 0 / 0 |
| skin | 0% | 0.48 | 7 / 1809 | 3% | 0.11 | 16 / 472 |
| liver | 0% | 0 | 0 / 226 | 2% | 0.03 | 7 / 406 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.02 | 1 / 80 |
| spleen | 0% | 0.39 | 1 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0.27 | 3 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0048167 | Biological process | regulation of synaptic plasticity |
| GO_0150037 | Biological process | regulation of calcium-dependent activation of synaptic vesicle fusion |
| GO_0016082 | Biological process | synaptic vesicle priming |
| GO_0007274 | Biological process | neuromuscular synaptic transmission |
| GO_0099509 | Biological process | regulation of presynaptic cytosolic calcium ion concentration |
| GO_0048790 | Biological process | maintenance of presynaptic active zone structure |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0098982 | Cellular component | GABA-ergic synapse |
| GO_0048786 | Cellular component | presynaptic active zone |
| GO_0048788 | Cellular component | cytoskeleton of presynaptic active zone |
| GO_0030426 | Cellular component | growth cone |
| GO_0042734 | Cellular component | presynaptic membrane |
| GO_0098882 | Molecular function | structural constituent of presynaptic active zone |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ERC2 |
| Protein name | ERC protein 2 ELKS/RAB6-interacting/CAST family member 2 |
| Synonyms | KIAA0378 |
| Description | FUNCTION: Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ. |
| Accessions | ENST00000288221.11 ENST00000460849.5 ENST00000492584.3 O15083 H7C4G9 |