Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 16 studies | 32% ± 11% | |
endothelial cell | 16 studies | 25% ± 10% | |
oligodendrocyte | 14 studies | 33% ± 11% | |
oligodendrocyte precursor cell | 13 studies | 32% ± 14% | |
glutamatergic neuron | 12 studies | 37% ± 23% | |
GABAergic neuron | 10 studies | 40% ± 21% | |
mast cell | 9 studies | 24% ± 7% | |
ciliated cell | 9 studies | 26% ± 8% | |
macrophage | 7 studies | 22% ± 6% | |
neuron | 7 studies | 30% ± 12% | |
interneuron | 7 studies | 44% ± 24% | |
microglial cell | 7 studies | 25% ± 7% | |
retinal rod cell | 7 studies | 30% ± 5% | |
endothelial cell of lymphatic vessel | 6 studies | 20% ± 4% | |
platelet | 6 studies | 27% ± 10% | |
epithelial cell | 6 studies | 44% ± 14% | |
retinal cone cell | 6 studies | 48% ± 21% | |
retinal bipolar neuron | 5 studies | 25% ± 9% | |
cardiac muscle cell | 5 studies | 31% ± 8% | |
Mueller cell | 5 studies | 40% ± 16% | |
goblet cell | 5 studies | 30% ± 18% | |
granule cell | 4 studies | 25% ± 5% | |
retinal ganglion cell | 4 studies | 40% ± 15% | |
basal cell | 4 studies | 31% ± 11% | |
retina horizontal cell | 4 studies | 25% ± 6% | |
fibroblast | 4 studies | 19% ± 2% | |
secretory cell | 3 studies | 20% ± 3% | |
GABAergic interneuron | 3 studies | 30% ± 5% | |
myeloid cell | 3 studies | 18% ± 2% | |
squamous epithelial cell | 3 studies | 31% ± 20% | |
club cell | 3 studies | 16% ± 1% | |
amacrine cell | 3 studies | 31% ± 7% | |
retinal pigment epithelial cell | 3 studies | 39% ± 17% | |
lymphocyte | 3 studies | 18% ± 2% | |
GABAergic amacrine cell | 3 studies | 26% ± 11% | |
OFF-bipolar cell | 3 studies | 26% ± 6% | |
ON-bipolar cell | 3 studies | 26% ± 8% | |
glycinergic amacrine cell | 3 studies | 21% ± 4% | |
rod bipolar cell | 3 studies | 32% ± 9% | |
abnormal cell | 3 studies | 20% ± 3% | |
neural progenitor cell | 3 studies | 27% ± 6% | |
enteroendocrine cell | 3 studies | 22% ± 5% | |
erythrocyte | 3 studies | 38% ± 10% | |
transit amplifying cell | 3 studies | 27% ± 14% | |
brush cell | 3 studies | 26% ± 12% | |
renal principal cell | 3 studies | 25% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 3664.70 | 245 / 245 | 100% | 75.57 | 501 / 502 |
brain | 100% | 6555.36 | 2641 / 2642 | 100% | 95.09 | 703 / 705 |
esophagus | 100% | 3638.30 | 1442 / 1445 | 99% | 44.68 | 182 / 183 |
intestine | 100% | 3526.97 | 966 / 966 | 99% | 53.98 | 521 / 527 |
adrenal gland | 100% | 5500.43 | 258 / 258 | 99% | 51.34 | 227 / 230 |
breast | 100% | 3005.63 | 459 / 459 | 98% | 55.84 | 1101 / 1118 |
kidney | 100% | 2961.99 | 89 / 89 | 98% | 46.17 | 886 / 901 |
skin | 100% | 5148.53 | 1809 / 1809 | 98% | 70.21 | 462 / 472 |
pancreas | 100% | 3394.25 | 328 / 328 | 98% | 46.54 | 174 / 178 |
stomach | 100% | 3129.62 | 358 / 359 | 98% | 44.23 | 279 / 286 |
bladder | 100% | 3764.57 | 21 / 21 | 97% | 40.83 | 489 / 504 |
lung | 98% | 2710.93 | 568 / 578 | 98% | 33.75 | 1129 / 1155 |
thymus | 100% | 3137.99 | 652 / 653 | 96% | 33.76 | 581 / 605 |
uterus | 99% | 2457.08 | 169 / 170 | 92% | 28.56 | 424 / 459 |
ovary | 100% | 2822.87 | 180 / 180 | 70% | 12.35 | 303 / 430 |
liver | 98% | 1787.18 | 221 / 226 | 68% | 15.81 | 275 / 406 |
adipose | 100% | 2732.68 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 2142.12 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 20.20 | 1 / 1 |
muscle | 99% | 2445.38 | 797 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 98% | 54.37 | 78 / 80 |
blood vessel | 97% | 1644.67 | 1294 / 1335 | 0% | 0 | 0 / 0 |
heart | 96% | 3516.12 | 823 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 33.04 | 43 / 45 |
lymph node | 0% | 0 | 0 / 0 | 59% | 11.09 | 17 / 29 |
peripheral blood | 52% | 1113.28 | 482 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0048388 | Biological process | endosomal lumen acidification |
GO_0008344 | Biological process | adult locomotory behavior |
GO_0045494 | Biological process | photoreceptor cell maintenance |
GO_1903428 | Biological process | positive regulation of reactive oxygen species biosynthetic process |
GO_0006885 | Biological process | regulation of pH |
GO_0006911 | Biological process | phagocytosis, engulfment |
GO_0097401 | Biological process | synaptic vesicle lumen acidification |
GO_1902476 | Biological process | chloride transmembrane transport |
GO_0051932 | Biological process | synaptic transmission, GABAergic |
GO_0045794 | Biological process | negative regulation of cell volume |
GO_0035249 | Biological process | synaptic transmission, glutamatergic |
GO_0032587 | Cellular component | ruffle membrane |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0031902 | Cellular component | late endosome membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0031410 | Cellular component | cytoplasmic vesicle |
GO_0012506 | Cellular component | vesicle membrane |
GO_0016020 | Cellular component | membrane |
GO_0055037 | Cellular component | recycling endosome |
GO_0005769 | Cellular component | early endosome |
GO_0031901 | Cellular component | early endosome membrane |
GO_0030672 | Cellular component | synaptic vesicle membrane |
GO_0043679 | Cellular component | axon terminus |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0042581 | Cellular component | specific granule |
GO_0098982 | Cellular component | GABA-ergic synapse |
GO_0009986 | Cellular component | cell surface |
GO_0000139 | Cellular component | Golgi membrane |
GO_0008021 | Cellular component | synaptic vesicle |
GO_0045335 | Cellular component | phagocytic vesicle |
GO_0005770 | Cellular component | late endosome |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0010008 | Cellular component | endosome membrane |
GO_0030141 | Cellular component | secretory granule |
GO_0005765 | Cellular component | lysosomal membrane |
GO_0072320 | Molecular function | volume-sensitive chloride channel activity |
GO_0015297 | Molecular function | antiporter activity |
GO_0030165 | Molecular function | PDZ domain binding |
GO_0005247 | Molecular function | voltage-gated chloride channel activity |
GO_0005524 | Molecular function | ATP binding |
GO_0005515 | Molecular function | protein binding |
GO_0005254 | Molecular function | chloride channel activity |
Gene name | CLCN3 |
Protein name | H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3) Chloride channel protein Chloride voltage-gated channel 3 CLCN3 protein |
Synonyms | |
Description | FUNCTION: [Isoform 1]: Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons (By similarity). The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons . The presence of conserved gating glutamate residues is typical for family members that function as antiporters . .; FUNCTION: [Isoform 2]: Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons. . |
Accessions | E9PE15 ENST00000511092.5 D6RDZ6 ENST00000513761.6 [P51790-1] ENST00000507875.6 P51790 H0Y8Z8 Q7Z4M4 ENST00000515420.1 ENST00000347613.9 [P51790-2] ENST00000360642.7 [P51790-4] ENST00000512813.5 D6RIX3 |