GO_0097401 | synaptic vesicle lumen acidification | OmnibusX

synaptic vesicle lumen acidification

I. Involved cell types

	Genes	Cell types	No. of supported studies
Group 1	ATP6V1G3 ATP6V0A4 ATP6V1E1 ATP6V1D ATP6V1G1 ATP6AP1 ATP6V1F ATP6AP2 ATP6V1A ATP6V1B1	renal alpha-intercalated cell	6 studies
Group 2	ATP6V1G2 ATP6V0A1 ATP6V1B2 ATP6V0D1 ATP6V1H CLCN3	amacrine cell retinal ganglion cell	6 studies
Group 3	ATP6V1C1	myeloid cell macrophage epithelial cell	44 studies

II. Literature review

Name	synaptic vesicle lumen acidification
ID	GO_0097401
collection_id	Biological process
Exact synonym	synaptic vesicle lumen pH reduction, synaptic vesicle proton loading
Description	The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading.
External URL
Genes	ATP6V1A ATP6V1E1 ATP6AP1 ATP6V1F ATP6V0A1 ATP6V0A4 ATP6V1G2 ATP6V1C1 ATP6V1H ATP6V0D1 ATP6V1G1 ATP6AP2 CLCN3 ATP6V1B2 ATP6V1G3 ATP6V1D ATP6V1B1