Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 36 studies | 34% ± 11% | |
classical monocyte | 24 studies | 34% ± 11% | |
monocyte | 20 studies | 34% ± 11% | |
non-classical monocyte | 19 studies | 32% ± 9% | |
conventional dendritic cell | 15 studies | 29% ± 11% | |
myeloid cell | 12 studies | 36% ± 11% | |
dendritic cell | 11 studies | 27% ± 10% | |
microglial cell | 10 studies | 28% ± 10% | |
alveolar macrophage | 8 studies | 30% ± 8% | |
neutrophil | 8 studies | 26% ± 7% | |
glutamatergic neuron | 8 studies | 44% ± 20% | |
mononuclear phagocyte | 6 studies | 35% ± 10% | |
epithelial cell of proximal tubule | 6 studies | 21% ± 5% | |
retinal cone cell | 6 studies | 37% ± 22% | |
retinal rod cell | 6 studies | 31% ± 15% | |
epithelial cell | 6 studies | 31% ± 13% | |
fibroblast | 6 studies | 21% ± 7% | |
leukocyte | 5 studies | 21% ± 2% | |
GABAergic neuron | 5 studies | 43% ± 18% | |
amacrine cell | 5 studies | 40% ± 19% | |
endothelial cell | 4 studies | 28% ± 9% | |
retinal ganglion cell | 4 studies | 73% ± 27% | |
retina horizontal cell | 4 studies | 49% ± 9% | |
basal cell | 4 studies | 25% ± 4% | |
inflammatory macrophage | 4 studies | 36% ± 16% | |
neuron | 4 studies | 33% ± 11% | |
interneuron | 4 studies | 42% ± 21% | |
plasmacytoid dendritic cell | 4 studies | 21% ± 3% | |
pancreatic A cell | 3 studies | 48% ± 21% | |
type B pancreatic cell | 3 studies | 50% ± 27% | |
retinal bipolar neuron | 3 studies | 38% ± 11% | |
GABAergic amacrine cell | 3 studies | 30% ± 11% | |
tissue-resident macrophage | 3 studies | 29% ± 2% | |
melanocyte | 3 studies | 39% ± 5% | |
intermediate monocyte | 3 studies | 44% ± 14% | |
oligodendrocyte precursor cell | 3 studies | 25% ± 0% | |
enteroendocrine cell | 3 studies | 30% ± 13% | |
astrocyte | 3 studies | 21% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
skin | 100% | 8410.53 | 1809 / 1809 | 100% | 162.93 | 472 / 472 |
esophagus | 100% | 5543.62 | 1444 / 1445 | 100% | 33.49 | 183 / 183 |
lung | 100% | 11022.48 | 578 / 578 | 100% | 46.20 | 1153 / 1155 |
thymus | 100% | 4683.96 | 652 / 653 | 100% | 57.38 | 604 / 605 |
breast | 100% | 5454.68 | 459 / 459 | 100% | 48.90 | 1114 / 1118 |
prostate | 100% | 3556.69 | 244 / 245 | 100% | 34.20 | 500 / 502 |
adrenal gland | 100% | 8218.79 | 258 / 258 | 99% | 141.61 | 228 / 230 |
brain | 99% | 14340.92 | 2618 / 2642 | 100% | 92.22 | 705 / 705 |
kidney | 100% | 6985.00 | 89 / 89 | 99% | 62.32 | 892 / 901 |
intestine | 100% | 5277.24 | 966 / 966 | 99% | 37.50 | 521 / 527 |
uterus | 99% | 4328.59 | 169 / 170 | 99% | 41.13 | 455 / 459 |
stomach | 99% | 3781.74 | 354 / 359 | 98% | 36.08 | 281 / 286 |
bladder | 100% | 4728.38 | 21 / 21 | 97% | 33.34 | 487 / 504 |
ovary | 100% | 3950.60 | 180 / 180 | 94% | 23.49 | 406 / 430 |
pancreas | 89% | 2681.88 | 292 / 328 | 98% | 44.44 | 175 / 178 |
liver | 96% | 2944.88 | 218 / 226 | 82% | 18.43 | 333 / 406 |
adipose | 100% | 6646.85 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 100.74 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 72.22 | 29 / 29 |
spleen | 100% | 9547.85 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 53.07 | 45 / 45 |
peripheral blood | 100% | 18292.57 | 926 / 929 | 0% | 0 | 0 / 0 |
muscle | 100% | 5332.29 | 799 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 5384.59 | 1328 / 1335 | 0% | 0 | 0 / 0 |
heart | 90% | 3382.13 | 779 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0046034 | Biological process | ATP metabolic process |
GO_0097401 | Biological process | synaptic vesicle lumen acidification |
GO_0007035 | Biological process | vacuolar acidification |
GO_0016241 | Biological process | regulation of macroautophagy |
GO_1902600 | Biological process | proton transmembrane transport |
GO_0001726 | Cellular component | ruffle |
GO_0005902 | Cellular component | microvillus |
GO_0016324 | Cellular component | apical plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0000221 | Cellular component | vacuolar proton-transporting V-type ATPase, V1 domain |
GO_0005829 | Cellular component | cytosol |
GO_0098850 | Cellular component | extrinsic component of synaptic vesicle membrane |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0005765 | Cellular component | lysosomal membrane |
GO_0042470 | Cellular component | melanosome |
GO_0030665 | Cellular component | clathrin-coated vesicle membrane |
GO_0046961 | Molecular function | proton-transporting ATPase activity, rotational mechanism |
GO_0015078 | Molecular function | proton transmembrane transporter activity |
GO_0005524 | Molecular function | ATP binding |
GO_0005515 | Molecular function | protein binding |
Gene name | ATP6V1B2 |
Protein name | V-type proton ATPase subunit B, brain isoform (V-ATPase subunit B 2) (Endomembrane proton pump 58 kDa subunit) (HO57) (Vacuolar proton pump subunit B 2) ATPase H+ transporting V1 subunit B2 |
Synonyms | ATP6B2 VPP3 |
Description | FUNCTION: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons . V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment . In renal intercalated cells, can partially compensate the lack of ATP6V1B1 and mediate secretion of protons (H+) into the urine under base-line conditions but not in conditions of acid load (By similarity). . |
Accessions | ENST00000276390.7 H0YC04 ENST00000523478.5 H0YC45 H0YAT8 E5RGH6 P21281 ENST00000520830.1 ENST00000521442.1 ENST00000519667.1 |