ATP6V1G1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0097401Biological processsynaptic vesicle lumen acidification
GO_0036295Biological processcellular response to increased oxygen levels
GO_0016241Biological processregulation of macroautophagy
GO_0006879Biological processintracellular iron ion homeostasis
GO_0016324Cellular componentapical plasma membrane
GO_1902495Cellular componenttransmembrane transporter complex
GO_0000221Cellular componentvacuolar proton-transporting V-type ATPase, V1 domain
GO_0030672Cellular componentsynaptic vesicle membrane
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005765Cellular componentlysosomal membrane
GO_0046961Molecular functionproton-transporting ATPase activity, rotational mechanism
GO_0005515Molecular functionprotein binding
GO_0016887Molecular functionATP hydrolysis activity
GO_0051117Molecular functionATPase binding

IV. Literature review

[source]
Gene nameATP6V1G1
Protein nameV-type proton ATPase subunit G 1 (V-ATPase subunit G 1) (V-ATPase 13 kDa subunit 1) (Vacuolar proton pump subunit G 1) (Vacuolar proton pump subunit M16)
ATPase H+ transporting V1 subunit G1
V-type proton ATPase subunit G
SynonymsATP6G1
ATP6G
ATP6J
DescriptionFUNCTION: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons . V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment . In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation . .

FUNCTION: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. .

FUNCTION: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. .

FUNCTION: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. .

AccessionsO75348
A0A7I2V375
ENST00000679150.1
A0A7I2V4K4
ENST00000677115.1
ENST00000374050.4
ENST00000677498.1
ENST00000473413.1
ENST00000678234.1
ENST00000677452.1
A0A7I2YQH3
A0A7I2V2N1
A0A7I2V3Q6