ATP6V1E1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1902600Biological processproton transmembrane transport
GO_0097401Biological processsynaptic vesicle lumen acidification
GO_0016241Biological processregulation of macroautophagy
GO_0005902Cellular componentmicrovillus
GO_0016324Cellular componentapical plasma membrane
GO_0000221Cellular componentvacuolar proton-transporting V-type ATPase, V1 domain
GO_0030672Cellular componentsynaptic vesicle membrane
GO_0016469Cellular componentproton-transporting two-sector ATPase complex
GO_0070062Cellular componentextracellular exosome
GO_0005768Cellular componentendosome
GO_0005829Cellular componentcytosol
GO_0030665Cellular componentclathrin-coated vesicle membrane
GO_0005765Cellular componentlysosomal membrane
GO_0046961Molecular functionproton-transporting ATPase activity, rotational mechanism
GO_0005515Molecular functionprotein binding
GO_0051117Molecular functionATPase binding

IV. Literature review

[source]
Gene nameATP6V1E1
Protein nameV-type proton ATPase subunit E 1 (V-type proton ATPase subunit e 1) (Vacuolar proton pump subunit E 1)
V-type proton ATPase subunit E 1 (V-ATPase subunit E 1) (V-ATPase 31 kDa subunit) (p31) (Vacuolar proton pump subunit E 1)
SynonymsATP6E2
ATP6E
hCG_21530
DescriptionFUNCTION: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons . V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment . .

AccessionsP36543
ENST00000413576.1
Q53Y06
ENST00000253413.10 [P36543-1]
ENST00000399796.6 [P36543-3]
C9J8H1
ENST00000399798.6 [P36543-2]