ATP6V1D report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0060271Biological processcilium assembly
GO_0061512Biological processprotein localization to cilium
GO_0048388Biological processendosomal lumen acidification
GO_0007042Biological processlysosomal lumen acidification
GO_0051452Biological processintracellular pH reduction
GO_0097401Biological processsynaptic vesicle lumen acidification
GO_0007035Biological processvacuolar acidification
GO_0061795Biological processGolgi lumen acidification
GO_0016241Biological processregulation of macroautophagy
GO_1902600Biological processproton transmembrane transport
GO_0035579Cellular componentspecific granule membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005813Cellular componentcentrosome
GO_1902495Cellular componenttransmembrane transporter complex
GO_0070062Cellular componentextracellular exosome
GO_0005654Cellular componentnucleoplasm
GO_0033176Cellular componentproton-transporting V-type ATPase complex
GO_0000221Cellular componentvacuolar proton-transporting V-type ATPase, V1 domain
GO_0000139Cellular componentGolgi membrane
GO_0005929Cellular componentcilium
GO_0005829Cellular componentcytosol
GO_0098850Cellular componentextrinsic component of synaptic vesicle membrane
GO_0010008Cellular componentendosome membrane
GO_0005765Cellular componentlysosomal membrane
GO_0030665Cellular componentclathrin-coated vesicle membrane
GO_0046961Molecular functionproton-transporting ATPase activity, rotational mechanism
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameATP6V1D
Protein nameV-type proton ATPase subunit D (V-ATPase subunit D) (V-ATPase 28 kDa accessory protein) (Vacuolar proton pump subunit D)
V-type proton ATPase subunit D (V-type proton ATPase subunit d) (Vacuolar proton pump subunit D)
ATPase H+ transporting V1 subunit D
SynonymsVATD
ATP6M
DescriptionFUNCTION: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons . V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium . .

AccessionsENST00000554236.5
Q8N5Z9
ENST00000216442.12
G3V2V6
G3V5S7
H0YJH8
ENST00000555012.1
Q6PJ05
ENST00000555723.5
ENST00000554087.5
H0YJS0
G3V341
ENST00000556058.5
G3V2S6
ENST00000555431.5
H0YJ55
ENST00000555625.5
ENST00000553687.1
G3V559
ENST00000553408.5
Q9Y5K8
ENST00000555474.5
G3V3T8