GO_0007042 | lysosomal lumen acidification

lysosomal lumen acidification

	Genes	Cell types	No. of supported studies
Group 1	TMEM199	B cell epithelial cell	4 studies
Group 2	GRN ATP6V0A1 RNASEK ATP6V1D LAMP1 LAMP2 ATP6AP1 ATP6AP2 ATP6V1F ATP6V1A CREG1 ATP6V0B	myeloid cell epithelial cell	5 studies
Group 3	CLN3 CLN5 ATP6V1H TMEM106B SNAPIN TMEM9 PPT1	epithelial cell	5 studies
Group 4	ATP6V0C CLN6	neuron hematopoietic stem cell	6 studies
Group 5	TCIRG1 CCDC115	dendritic cell non-classical monocyte conventional dendritic cell	10 studies

Name	lysosomal lumen acidification
ID	GO_0007042
collection_id	Biological process
Exact synonym	lysosome pH reduction
Description	Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.
External URL
Genes	vatpase_atp6v0a1_human ATP6V0C SNAPIN TMEM199 TMEM106B ATP6AP2 CLN3 TMEM9 ATP6V1F GRN vatpase_atp6v0a3_human ATP6V1H CREG1 LAMP1 ATP6V0B CLN6 RNASEK ATP6V1A ATP6AP1 TCIRG1 ATP6V0A1 CLN5 CCDC115 PPT1 LAMP2 ATP6V1D