Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 6021.44 | 459 / 459 | 100% | 338.62 | 1118 / 1118 |
brain | 100% | 7657.84 | 2641 / 2642 | 100% | 267.22 | 705 / 705 |
thymus | 100% | 4845.87 | 653 / 653 | 100% | 159.26 | 604 / 605 |
lung | 100% | 8020.40 | 578 / 578 | 100% | 215.05 | 1153 / 1155 |
ovary | 100% | 5221.48 | 180 / 180 | 100% | 188.24 | 429 / 430 |
prostate | 100% | 5244.67 | 245 / 245 | 100% | 163.00 | 500 / 502 |
uterus | 100% | 7039.46 | 170 / 170 | 100% | 168.03 | 457 / 459 |
skin | 100% | 4649.02 | 1803 / 1809 | 99% | 240.83 | 469 / 472 |
bladder | 100% | 5946.95 | 21 / 21 | 99% | 152.64 | 499 / 504 |
stomach | 100% | 3682.92 | 359 / 359 | 98% | 117.44 | 280 / 286 |
intestine | 100% | 5163.65 | 963 / 966 | 98% | 113.43 | 517 / 527 |
esophagus | 99% | 4249.55 | 1432 / 1445 | 98% | 163.91 | 180 / 183 |
adrenal gland | 100% | 4895.20 | 258 / 258 | 97% | 115.09 | 224 / 230 |
kidney | 100% | 4554.10 | 89 / 89 | 96% | 167.77 | 869 / 901 |
pancreas | 97% | 2466.80 | 317 / 328 | 99% | 128.22 | 176 / 178 |
liver | 42% | 759.04 | 94 / 226 | 64% | 49.08 | 260 / 406 |
adipose | 100% | 5526.50 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 156.54 | 29 / 29 |
spleen | 100% | 12753.98 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 164.15 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 134.08 | 1 / 1 |
blood vessel | 100% | 6950.23 | 1334 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 100% | 15254.88 | 926 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 95% | 112.78 | 76 / 80 |
heart | 93% | 2662.03 | 805 / 861 | 0% | 0 | 0 / 0 |
muscle | 64% | 997.98 | 510 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007601 | Biological process | visual perception |
GO_0007625 | Biological process | grooming behavior |
GO_0048549 | Biological process | positive regulation of pinocytosis |
GO_0006898 | Biological process | receptor-mediated endocytosis |
GO_0007042 | Biological process | lysosomal lumen acidification |
GO_0007269 | Biological process | neurotransmitter secretion |
GO_0008344 | Biological process | adult locomotory behavior |
GO_0008306 | Biological process | associative learning |
GO_0006907 | Biological process | pinocytosis |
GO_0016042 | Biological process | lipid catabolic process |
GO_0048260 | Biological process | positive regulation of receptor-mediated endocytosis |
GO_0030149 | Biological process | sphingolipid catabolic process |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0048666 | Biological process | neuron development |
GO_0030163 | Biological process | protein catabolic process |
GO_0002084 | Biological process | protein depalmitoylation |
GO_0034164 | Biological process | negative regulation of toll-like receptor 9 signaling pathway |
GO_0007420 | Biological process | brain development |
GO_0015031 | Biological process | protein transport |
GO_0046949 | Biological process | fatty-acyl-CoA biosynthetic process |
GO_0043524 | Biological process | negative regulation of neuron apoptotic process |
GO_0031579 | Biological process | membrane raft organization |
GO_0007399 | Biological process | nervous system development |
GO_0050803 | Biological process | regulation of synapse structure or activity |
GO_0030308 | Biological process | negative regulation of cell growth |
GO_0005576 | Cellular component | extracellular region |
GO_0045121 | Cellular component | membrane raft |
GO_0016020 | Cellular component | membrane |
GO_0005764 | Cellular component | lysosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0043025 | Cellular component | neuronal cell body |
GO_0030425 | Cellular component | dendrite |
GO_0005829 | Cellular component | cytosol |
GO_0008021 | Cellular component | synaptic vesicle |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0043202 | Cellular component | lysosomal lumen |
GO_0030424 | Cellular component | axon |
GO_0005765 | Cellular component | lysosomal membrane |
GO_0005634 | Cellular component | nucleus |
GO_0052816 | Molecular function | long-chain fatty acyl-CoA hydrolase activity |
GO_0008474 | Molecular function | palmitoyl-(protein) hydrolase activity |
GO_0035727 | Molecular function | lysophosphatidic acid binding |
GO_0005515 | Molecular function | protein binding |
GO_0120146 | Molecular function | sulfatide binding |
Gene name | PPT1 |
Protein name | Palmitoyl-protein thioesterase 1 Palmitoyl-protein thioesterase 1 (PPT-1) (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1) Palmitoyl-protein thioesterase 1 (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1) |
Synonyms | PPT CLN1 |
Description | FUNCTION: Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons . . |
Accessions | A0A286YF39 A0A286YFE3 ENST00000642050.2 [P50897-1] ENST00000641381.1 ENST00000449045.7 [P50897-2] ENST00000641548.1 ENST00000526547.2 ENST00000641083.1 ENST00000641691.1 P50897 ENST00000372779.9 E9PP28 E9PMG2 ENST00000530704.6 Q5T0S4 ENST00000641924.1 ENST00000641319.1 E9PIA8 A0A286YEP3 ENST00000529905.5 [P50897-1] ENST00000530076.6 E9PSE5 E9PK48 ENST00000439754.6 A0A286YFF7 ENST00000641471.1 ENST00000527311.7 A0A286YFL8 A0A286YFL6 A0A2C9F2P4 ENST00000433473.8 |