PPT1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007601Biological processvisual perception
GO_0007625Biological processgrooming behavior
GO_0048549Biological processpositive regulation of pinocytosis
GO_0006898Biological processreceptor-mediated endocytosis
GO_0007042Biological processlysosomal lumen acidification
GO_0007269Biological processneurotransmitter secretion
GO_0008344Biological processadult locomotory behavior
GO_0008306Biological processassociative learning
GO_0006907Biological processpinocytosis
GO_0016042Biological processlipid catabolic process
GO_0048260Biological processpositive regulation of receptor-mediated endocytosis
GO_0030149Biological processsphingolipid catabolic process
GO_0043066Biological processnegative regulation of apoptotic process
GO_0048666Biological processneuron development
GO_0030163Biological processprotein catabolic process
GO_0002084Biological processprotein depalmitoylation
GO_0034164Biological processnegative regulation of toll-like receptor 9 signaling pathway
GO_0007420Biological processbrain development
GO_0015031Biological processprotein transport
GO_0046949Biological processfatty-acyl-CoA biosynthetic process
GO_0043524Biological processnegative regulation of neuron apoptotic process
GO_0031579Biological processmembrane raft organization
GO_0007399Biological processnervous system development
GO_0050803Biological processregulation of synapse structure or activity
GO_0030308Biological processnegative regulation of cell growth
GO_0005576Cellular componentextracellular region
GO_0045121Cellular componentmembrane raft
GO_0016020Cellular componentmembrane
GO_0005764Cellular componentlysosome
GO_0070062Cellular componentextracellular exosome
GO_0005794Cellular componentGolgi apparatus
GO_0043025Cellular componentneuronal cell body
GO_0030425Cellular componentdendrite
GO_0005829Cellular componentcytosol
GO_0008021Cellular componentsynaptic vesicle
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0043202Cellular componentlysosomal lumen
GO_0030424Cellular componentaxon
GO_0005765Cellular componentlysosomal membrane
GO_0005634Cellular componentnucleus
GO_0052816Molecular functionlong-chain fatty acyl-CoA hydrolase activity
GO_0008474Molecular functionpalmitoyl-(protein) hydrolase activity
GO_0035727Molecular functionlysophosphatidic acid binding
GO_0005515Molecular functionprotein binding
GO_0120146Molecular functionsulfatide binding

IV. Literature review

[source]
Gene namePPT1
Protein namePalmitoyl-protein thioesterase 1
Palmitoyl-protein thioesterase 1 (PPT-1) (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1)
Palmitoyl-protein thioesterase 1 (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1)
SynonymsPPT
CLN1
DescriptionFUNCTION: Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons . .

AccessionsA0A286YF39
A0A286YFE3
ENST00000642050.2 [P50897-1]
ENST00000641381.1
ENST00000449045.7 [P50897-2]
ENST00000641548.1
ENST00000526547.2
ENST00000641083.1
ENST00000641691.1
P50897
ENST00000372779.9
E9PP28
E9PMG2
ENST00000530704.6
Q5T0S4
ENST00000641924.1
ENST00000641319.1
E9PIA8
A0A286YEP3
ENST00000529905.5 [P50897-1]
ENST00000530076.6
E9PSE5
E9PK48
ENST00000439754.6
A0A286YFF7
ENST00000641471.1
ENST00000527311.7
A0A286YFL8
A0A286YFL6
A0A2C9F2P4
ENST00000433473.8