Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 16 studies | 51% ± 16% | |
astrocyte | 16 studies | 42% ± 17% | |
oligodendrocyte precursor cell | 15 studies | 64% ± 20% | |
glutamatergic neuron | 13 studies | 78% ± 24% | |
GABAergic neuron | 11 studies | 73% ± 21% | |
amacrine cell | 8 studies | 66% ± 26% | |
retinal rod cell | 8 studies | 59% ± 29% | |
interneuron | 7 studies | 70% ± 25% | |
microglial cell | 7 studies | 38% ± 18% | |
retinal cone cell | 7 studies | 66% ± 24% | |
retina horizontal cell | 6 studies | 51% ± 23% | |
neuron | 5 studies | 62% ± 16% | |
endothelial cell | 5 studies | 48% ± 20% | |
retinal bipolar neuron | 5 studies | 50% ± 26% | |
retinal ganglion cell | 5 studies | 60% ± 30% | |
smooth muscle cell | 5 studies | 30% ± 15% | |
granule cell | 4 studies | 71% ± 17% | |
pericyte | 4 studies | 34% ± 16% | |
OFF-bipolar cell | 4 studies | 62% ± 33% | |
ON-bipolar cell | 4 studies | 58% ± 33% | |
GABAergic interneuron | 3 studies | 82% ± 1% | |
GABAergic amacrine cell | 3 studies | 94% ± 6% | |
glycinergic amacrine cell | 3 studies | 74% ± 8% | |
rod bipolar cell | 3 studies | 48% ± 20% | |
neural progenitor cell | 3 studies | 41% ± 4% | |
ependymal cell | 3 studies | 48% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 1863.56 | 2638 / 2642 | 87% | 6.80 | 616 / 705 |
blood vessel | 99% | 805.64 | 1323 / 1335 | 0% | 0 | 0 / 0 |
prostate | 51% | 157.10 | 126 / 245 | 42% | 4.72 | 210 / 502 |
uterus | 65% | 243.92 | 110 / 170 | 9% | 0.28 | 40 / 459 |
adrenal gland | 16% | 78.66 | 42 / 258 | 50% | 3.87 | 116 / 230 |
bladder | 57% | 127.76 | 12 / 21 | 3% | 0.07 | 13 / 504 |
adipose | 54% | 154.41 | 652 / 1204 | 0% | 0 | 0 / 0 |
breast | 37% | 86.29 | 168 / 459 | 6% | 0.15 | 62 / 1118 |
ovary | 34% | 91.31 | 62 / 180 | 1% | 0.03 | 4 / 430 |
thymus | 33% | 70.90 | 216 / 653 | 0% | 0 | 0 / 605 |
pancreas | 0% | 0.48 | 1 / 328 | 29% | 0.47 | 52 / 178 |
kidney | 17% | 54.51 | 15 / 89 | 5% | 0.11 | 48 / 901 |
intestine | 16% | 33.72 | 154 / 966 | 4% | 0.07 | 20 / 527 |
lung | 15% | 31.26 | 86 / 578 | 4% | 0.09 | 51 / 1155 |
skin | 15% | 36.05 | 266 / 1809 | 4% | 0.10 | 18 / 472 |
esophagus | 14% | 39.90 | 202 / 1445 | 4% | 0.09 | 7 / 183 |
stomach | 8% | 15.68 | 28 / 359 | 5% | 0.12 | 13 / 286 |
eye | 0% | 0 | 0 / 0 | 3% | 0.12 | 2 / 80 |
heart | 2% | 3.32 | 15 / 861 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 1% | 0.02 | 4 / 406 |
muscle | 0% | 1.02 | 4 / 803 | 0% | 0 | 0 / 0 |
spleen | 0% | 0.59 | 1 / 241 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0099519 | Biological process | dense core granule cytoskeletal transport |
GO_0007160 | Biological process | cell-matrix adhesion |
GO_0060998 | Biological process | regulation of dendritic spine development |
GO_0061001 | Biological process | regulation of dendritic spine morphogenesis |
GO_0099172 | Biological process | presynapse organization |
GO_0050808 | Biological process | synapse organization |
GO_2000300 | Biological process | regulation of synaptic vesicle exocytosis |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0043197 | Cellular component | dendritic spine |
GO_0070062 | Cellular component | extracellular exosome |
GO_0042734 | Cellular component | presynaptic membrane |
GO_0009986 | Cellular component | cell surface |
GO_0048786 | Cellular component | presynaptic active zone |
GO_0005829 | Cellular component | cytosol |
GO_0008021 | Cellular component | synaptic vesicle |
GO_0005737 | Cellular component | cytoplasm |
GO_0099572 | Cellular component | postsynaptic specialization |
GO_0030424 | Cellular component | axon |
GO_0099181 | Molecular function | structural constituent of presynapse |
GO_0005515 | Molecular function | protein binding |
Gene name | PPFIA2 |
Protein name | Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2) PTPRF interacting protein alpha 2 PPFIA2 variant protein |
Synonyms | protein variant |
Description | FUNCTION: Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. In neuronal cells, is a scaffolding protein in the dendritic spines which acts as immobile postsynaptic post able to recruit KIF1A-driven dense core vesicles to dendritic spines . . |
Accessions | ENST00000551147.1 H0YIJ4 ENST00000443686.7 [O75334-6] ENST00000548586.5 [O75334-3] ENST00000541570.6 [O75334-7] ENST00000548670.1 ENST00000552948.5 [O75334-4] H0YHJ4 ENST00000547623.5 ENST00000550359.6 ENST00000407050.8 [O75334-5] ENST00000550584.6 Q4LE62 ENST00000549396.6 [O75334-1] H0YHK3 ENST00000549325.5 [O75334-2] F8VWG6 F8VWR9 ENST00000553058.5 H0YH95 ENST00000550018.5 ENST00000541017.5 [O75334-8] O75334 F8W1Y8 G3V200 F8VU88 ENST00000551461.5 F8VYK7 ENST00000333447.11 [O75334-6] ENST00000551442.5 ENST00000548790.1 |