Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 11 studies | 51% ± 22% | |
platelet | 10 studies | 54% ± 19% | |
adipocyte | 10 studies | 64% ± 15% | |
pericyte | 9 studies | 25% ± 10% | |
neuron | 7 studies | 32% ± 12% | |
GABAergic neuron | 7 studies | 46% ± 14% | |
interneuron | 6 studies | 41% ± 15% | |
oligodendrocyte precursor cell | 6 studies | 21% ± 7% | |
endothelial cell | 5 studies | 35% ± 16% | |
smooth muscle cell | 4 studies | 21% ± 3% | |
respiratory goblet cell | 4 studies | 20% ± 2% | |
megakaryocyte | 4 studies | 61% ± 18% | |
retinal cone cell | 4 studies | 25% ± 4% | |
megakaryocyte-erythroid progenitor cell | 4 studies | 40% ± 11% | |
GABAergic interneuron | 3 studies | 34% ± 16% | |
granule cell | 3 studies | 19% ± 4% | |
ON-bipolar cell | 3 studies | 17% ± 1% | |
glycinergic amacrine cell | 3 studies | 19% ± 3% | |
fibroblast | 3 studies | 26% ± 9% | |
erythrocyte | 3 studies | 31% ± 9% | |
erythroblast | 3 studies | 44% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 99% | 9339.36 | 456 / 459 | 97% | 48.44 | 1084 / 1118 |
adrenal gland | 100% | 7701.27 | 258 / 258 | 94% | 50.81 | 217 / 230 |
brain | 95% | 3248.84 | 2515 / 2642 | 98% | 22.15 | 690 / 705 |
prostate | 92% | 1761.35 | 225 / 245 | 97% | 20.80 | 489 / 502 |
ovary | 100% | 4666.26 | 180 / 180 | 87% | 12.81 | 376 / 430 |
lung | 89% | 1388.38 | 512 / 578 | 74% | 10.51 | 850 / 1155 |
bladder | 100% | 3999.71 | 21 / 21 | 51% | 6.57 | 256 / 504 |
uterus | 95% | 1512.47 | 161 / 170 | 51% | 8.17 | 233 / 459 |
intestine | 94% | 1970.01 | 912 / 966 | 49% | 5.28 | 259 / 527 |
esophagus | 78% | 4376.13 | 1132 / 1445 | 61% | 8.10 | 111 / 183 |
stomach | 73% | 1249.26 | 263 / 359 | 52% | 6.36 | 150 / 286 |
pancreas | 27% | 282.08 | 88 / 328 | 80% | 10.86 | 143 / 178 |
adipose | 100% | 14426.00 | 1201 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 2438.36 | 240 / 241 | 0% | 0 | 0 / 0 |
kidney | 47% | 744.76 | 42 / 89 | 52% | 5.24 | 466 / 901 |
skin | 19% | 229.72 | 335 / 1809 | 80% | 16.37 | 379 / 472 |
lymph node | 0% | 0 | 0 / 0 | 79% | 21.59 | 23 / 29 |
heart | 77% | 1496.08 | 662 / 861 | 0% | 0 | 0 / 0 |
thymus | 31% | 409.11 | 203 / 653 | 46% | 3.32 | 277 / 605 |
tonsil | 0% | 0 | 0 / 0 | 62% | 9.01 | 28 / 45 |
peripheral blood | 35% | 546.13 | 324 / 929 | 0% | 0 | 0 / 0 |
blood vessel | 31% | 764.80 | 416 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 15% | 1.00 | 12 / 80 |
liver | 1% | 7.39 | 2 / 226 | 9% | 0.87 | 36 / 406 |
muscle | 1% | 12.70 | 8 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0050804 | Biological process | modulation of chemical synaptic transmission |
GO_0007612 | Biological process | learning |
GO_0001932 | Biological process | regulation of protein phosphorylation |
GO_0006631 | Biological process | fatty acid metabolic process |
GO_0141162 | Biological process | negative regulation of cAMP/PKA signal transduction |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0097332 | Biological process | response to antipsychotic drug |
GO_2000480 | Biological process | negative regulation of cAMP-dependent protein kinase activity |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0043197 | Cellular component | dendritic spine |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0043198 | Cellular component | dendritic shaft |
GO_0005813 | Cellular component | centrosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0043025 | Cellular component | neuronal cell body |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0097546 | Cellular component | ciliary base |
GO_0005952 | Cellular component | cAMP-dependent protein kinase complex |
GO_0030552 | Molecular function | cAMP binding |
GO_0004862 | Molecular function | cAMP-dependent protein kinase inhibitor activity |
GO_0019904 | Molecular function | protein domain specific binding |
GO_0008603 | Molecular function | cAMP-dependent protein kinase regulator activity |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
GO_0034236 | Molecular function | protein kinase A catalytic subunit binding |
GO_0005515 | Molecular function | protein binding |
Gene name | PRKAR2B |
Protein name | Protein kinase, cAMP-dependent, regulatory, type II, beta Type II cAMP-dependent regulatory protein kinase beta Protein kinase cAMP-dependent type II regulatory subunit beta cAMP-dependent protein kinase type II-beta regulatory subunit Uncharacterized protein PRKAR2B |
Synonyms | |
Description | FUNCTION: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. |
Accessions | P31323 A0A9L9PXN2 A3R6R8 Q75MP1 ENST00000265717.5 Q6DHZ2 ENST00000706581.1 |