PRKAR2B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0050804Biological processmodulation of chemical synaptic transmission
GO_0007612Biological processlearning
GO_0001932Biological processregulation of protein phosphorylation
GO_0006631Biological processfatty acid metabolic process
GO_0141162Biological processnegative regulation of cAMP/PKA signal transduction
GO_0035556Biological processintracellular signal transduction
GO_0097332Biological processresponse to antipsychotic drug
GO_2000480Biological processnegative regulation of cAMP-dependent protein kinase activity
GO_0098978Cellular componentglutamatergic synapse
GO_0005886Cellular componentplasma membrane
GO_0043197Cellular componentdendritic spine
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0043198Cellular componentdendritic shaft
GO_0005813Cellular componentcentrosome
GO_0070062Cellular componentextracellular exosome
GO_0043025Cellular componentneuronal cell body
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0097546Cellular componentciliary base
GO_0005952Cellular componentcAMP-dependent protein kinase complex
GO_0030552Molecular functioncAMP binding
GO_0004862Molecular functioncAMP-dependent protein kinase inhibitor activity
GO_0019904Molecular functionprotein domain specific binding
GO_0008603Molecular functioncAMP-dependent protein kinase regulator activity
GO_0031625Molecular functionubiquitin protein ligase binding
GO_0034236Molecular functionprotein kinase A catalytic subunit binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePRKAR2B
Protein nameProtein kinase, cAMP-dependent, regulatory, type II, beta
Type II cAMP-dependent regulatory protein kinase beta
Protein kinase cAMP-dependent type II regulatory subunit beta
cAMP-dependent protein kinase type II-beta regulatory subunit
Uncharacterized protein PRKAR2B
Synonyms
DescriptionFUNCTION: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.

AccessionsP31323
A0A9L9PXN2
A3R6R8
Q75MP1
ENST00000265717.5
Q6DHZ2
ENST00000706581.1