Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 5 studies | 30% ± 10% | |
| amacrine cell | 4 studies | 25% ± 6% | |
| glutamatergic neuron | 4 studies | 38% ± 19% | |
| retinal bipolar neuron | 3 studies | 17% ± 1% | |
| neuron | 3 studies | 26% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 27% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 94% | 15695.39 | 2488 / 2642 | 100% | 29.86 | 702 / 705 |
| prostate | 96% | 4778.08 | 234 / 245 | 74% | 4.32 | 373 / 502 |
| ovary | 100% | 12793.16 | 180 / 180 | 37% | 1.83 | 159 / 430 |
| uterus | 99% | 8336.69 | 168 / 170 | 32% | 2.60 | 149 / 459 |
| adrenal gland | 53% | 939.10 | 136 / 258 | 72% | 10.38 | 166 / 230 |
| breast | 49% | 996.66 | 223 / 459 | 69% | 5.11 | 769 / 1118 |
| intestine | 90% | 2885.05 | 868 / 966 | 18% | 0.62 | 97 / 527 |
| bladder | 86% | 3730.24 | 18 / 21 | 17% | 0.86 | 88 / 504 |
| lung | 66% | 1231.71 | 381 / 578 | 30% | 1.49 | 348 / 1155 |
| blood vessel | 96% | 4673.07 | 1282 / 1335 | 0% | 0 | 0 / 0 |
| thymus | 53% | 1006.37 | 345 / 653 | 37% | 1.43 | 224 / 605 |
| esophagus | 63% | 2285.86 | 917 / 1445 | 23% | 0.98 | 42 / 183 |
| kidney | 28% | 455.18 | 25 / 89 | 40% | 1.97 | 363 / 901 |
| pancreas | 2% | 18.93 | 5 / 328 | 53% | 2.60 | 95 / 178 |
| stomach | 34% | 871.20 | 123 / 359 | 21% | 0.63 | 59 / 286 |
| adipose | 48% | 1084.31 | 580 / 1204 | 0% | 0 | 0 / 0 |
| skin | 9% | 136.23 | 158 / 1809 | 30% | 1.66 | 141 / 472 |
| heart | 33% | 613.19 | 281 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 9% | 0.29 | 4 / 45 |
| eye | 0% | 0 | 0 / 0 | 5% | 0.20 | 4 / 80 |
| liver | 0% | 0 | 0 / 226 | 5% | 0.16 | 19 / 406 |
| muscle | 2% | 33.62 | 17 / 803 | 0% | 0 | 0 / 0 |
| spleen | 0% | 5.04 | 1 / 241 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0031629 | Biological process | synaptic vesicle fusion to presynaptic active zone membrane |
| GO_0150037 | Biological process | regulation of calcium-dependent activation of synaptic vesicle fusion |
| GO_1905513 | Biological process | negative regulation of short-term synaptic potentiation |
| GO_0050884 | Biological process | neuromuscular process controlling posture |
| GO_0035544 | Biological process | negative regulation of SNARE complex assembly |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0098839 | Cellular component | postsynaptic density membrane |
| GO_0030672 | Cellular component | synaptic vesicle membrane |
| GO_0098793 | Cellular component | presynapse |
| GO_0043679 | Cellular component | axon terminus |
| GO_0008021 | Cellular component | synaptic vesicle |
| GO_0042734 | Cellular component | presynaptic membrane |
| GO_0031982 | Cellular component | vesicle |
| GO_0043197 | Cellular component | dendritic spine |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0017075 | Molecular function | syntaxin-1 binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | PRRT2 |
| Protein name | Proline rich transmembrane protein 2 Proline-rich transmembrane protein 2 (Dispanin subfamily B member 3) (DSPB3) |
| Synonyms | |
| Description | FUNCTION: As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca(2+)-sensing. In the cerebellum, may inhibit SNARE complex formation and down-regulate short-term facilitation. . |
| Accessions | A0A1B0GTP1 ENST00000637565.1 ENST00000636619.1 ENST00000358758.12 [Q7Z6L0-1] A0A1B0GTS0 ENST00000637064.1 [Q7Z6L0-1] ENST00000647876.1 [Q7Z6L0-3] ENST00000637290.1 ENST00000636902.1 ENST00000637403.1 ENST00000567659.3 [Q7Z6L0-2] A0A1B0GUW9 ENST00000636131.1 [Q7Z6L0-3] ENST00000637596.1 ENST00000567551.2 A0A1B0GU37 A0A1B0GU25 A0A1B0GTE9 A0A1B0GTR2 Q7Z6L0 H3BN10 ENST00000300797.7 [Q7Z6L0-3] ENST00000636246.1 ENST00000572820.2 [Q7Z6L0-1] A0A1B0GUR0 ENST00000562148.2 |
