I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| neuron | 4 studies | 17% ± 1% | |
| glutamatergic neuron | 4 studies | 42% ± 19% | |
| GABAergic neuron | 3 studies | 36% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| neuron | 4 studies | 17% ± 1% | |
| glutamatergic neuron | 4 studies | 42% ± 19% | |
| GABAergic neuron | 3 studies | 36% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 29% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 89% | 13878.69 | 2343 / 2642 | 87% | 30.21 | 615 / 705 |
| adrenal gland | 95% | 4405.53 | 246 / 258 | 79% | 19.48 | 181 / 230 |
| pancreas | 83% | 2866.38 | 272 / 328 | 89% | 18.21 | 158 / 178 |
| prostate | 64% | 2923.17 | 158 / 245 | 100% | 68.16 | 502 / 502 |
| kidney | 99% | 7667.10 | 88 / 89 | 32% | 9.47 | 289 / 901 |
| esophagus | 39% | 4352.00 | 557 / 1445 | 91% | 38.24 | 166 / 183 |
| skin | 72% | 17370.09 | 1305 / 1809 | 56% | 10.82 | 265 / 472 |
| liver | 79% | 3273.43 | 178 / 226 | 48% | 7.30 | 194 / 406 |
| breast | 14% | 442.37 | 65 / 459 | 87% | 25.15 | 969 / 1118 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 38.42 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 37.17 | 1 / 1 |
| eye | 0% | 0 | 0 / 0 | 98% | 20.72 | 78 / 80 |
| ovary | 0% | 0 | 0 / 180 | 97% | 30.84 | 417 / 430 |
| uterus | 4% | 226.72 | 7 / 170 | 91% | 33.09 | 417 / 459 |
| lung | 0% | 3.54 | 1 / 578 | 87% | 20.08 | 1001 / 1155 |
| bladder | 0% | 0 | 0 / 21 | 83% | 16.28 | 416 / 504 |
| intestine | 0% | 2.83 | 1 / 966 | 76% | 13.08 | 402 / 527 |
| stomach | 1% | 30.27 | 4 / 359 | 69% | 12.53 | 198 / 286 |
| thymus | 0% | 8.93 | 1 / 653 | 47% | 5.74 | 286 / 605 |
| lymph node | 0% | 0 | 0 / 0 | 17% | 2.01 | 5 / 29 |
| adipose | 0% | 20.13 | 6 / 1204 | 0% | 0 | 0 / 0 |
| heart | 0% | 7.61 | 3 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 5.36 | 2 / 929 | 0% | 0 | 0 / 0 |
| muscle | 0% | 4.67 | 1 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 8.24 | 1 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| GO_0099173 | Biological process | postsynapse organization |
| GO_0021692 | Biological process | cerebellar Purkinje cell layer morphogenesis |
| GO_0099150 | Biological process | regulation of postsynaptic specialization assembly |
| GO_0035264 | Biological process | multicellular organism growth |
| GO_0051693 | Biological process | actin filament capping |
| GO_0030036 | Biological process | actin cytoskeleton organization |
| GO_0016192 | Biological process | vesicle-mediated transport |
| GO_0030534 | Biological process | adult behavior |
| GO_0007416 | Biological process | synapse assembly |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0005615 | Cellular component | extracellular space |
| GO_0098793 | Cellular component | presynapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0099189 | Cellular component | postsynaptic spectrin-associated cytoskeleton |
| GO_0030864 | Cellular component | cortical actin cytoskeleton |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0005829 | Cellular component | cytosol |
| GO_0033010 | Cellular component | paranodal junction |
| GO_0042995 | Cellular component | cell projection |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0030054 | Cellular component | cell junction |
| GO_0098688 | Cellular component | parallel fiber to Purkinje cell synapse |
| GO_0008091 | Cellular component | spectrin |
| GO_0005543 | Molecular function | phospholipid binding |
| GO_0045296 | Molecular function | cadherin binding |
| GO_0005200 | Molecular function | structural constituent of cytoskeleton |
| GO_0051015 | Molecular function | actin filament binding |
| GO_0099186 | Molecular function | structural constituent of postsynapse |
| GO_0098918 | Molecular function | structural constituent of synapse |
| GO_0003779 | Molecular function | actin binding |
| Gene name | SPTBN2 |
| Protein name | SPTBN2 protein (Spectrin beta chain, non-erythrocytic 2) Spectrin beta chain SPTBN2 protein Mutant beta-III spectrin protein Spectrin beta III sigma 2 Spectrin beta chain, non-erythrocytic 2 (Beta-III spectrin) (Spinocerebellar ataxia 5 protein) |
| Synonyms | KIAA0302 SCA5 |
| Description | FUNCTION: Probably plays an important role in neuronal membrane skeleton. |
| Accessions | ENST00000647510.2 [O15020-1] Q45KQ1 ENST00000617502.5 ENST00000611817 A0A087WYQ1 ENST00000533211.6 [O15020-1] ENST00000309996.7 [O15020-1] O15020 C1KC08 ENST00000529997.5 [O15020-2] A0A096XMD7 A4QPE4 ENST00000611817.5 [O15020-1] |
