Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 17 studies | 44% ± 19% | |
astrocyte | 16 studies | 85% ± 18% | |
oligodendrocyte precursor cell | 14 studies | 67% ± 25% | |
glutamatergic neuron | 12 studies | 86% ± 19% | |
GABAergic neuron | 11 studies | 82% ± 19% | |
microglial cell | 9 studies | 45% ± 19% | |
endothelial cell of lymphatic vessel | 8 studies | 48% ± 20% | |
oligodendrocyte | 7 studies | 45% ± 24% | |
neuron | 6 studies | 61% ± 21% | |
interneuron | 6 studies | 70% ± 31% | |
type I pneumocyte | 5 studies | 39% ± 8% | |
Mueller cell | 4 studies | 59% ± 10% | |
amacrine cell | 4 studies | 94% ± 4% | |
retinal cone cell | 4 studies | 73% ± 18% | |
retinal ganglion cell | 4 studies | 92% ± 6% | |
GABAergic interneuron | 3 studies | 93% ± 7% | |
granule cell | 3 studies | 58% ± 31% | |
vein endothelial cell | 3 studies | 41% ± 26% | |
GABAergic amacrine cell | 3 studies | 92% ± 7% | |
OFF-bipolar cell | 3 studies | 87% ± 12% | |
ON-bipolar cell | 3 studies | 92% ± 10% | |
glycinergic amacrine cell | 3 studies | 88% ± 8% | |
retinal pigment epithelial cell | 3 studies | 45% ± 17% | |
ependymal cell | 3 studies | 86% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 98% | 999.39 | 2599 / 2642 | 92% | 13.40 | 651 / 705 |
kidney | 46% | 57.04 | 41 / 89 | 80% | 3.60 | 721 / 901 |
eye | 0% | 0 | 0 / 0 | 90% | 11.88 | 72 / 80 |
skin | 28% | 40.38 | 504 / 1809 | 57% | 8.12 | 268 / 472 |
adrenal gland | 28% | 27.56 | 71 / 258 | 45% | 1.84 | 104 / 230 |
pancreas | 0% | 0 | 0 / 328 | 65% | 3.61 | 116 / 178 |
lung | 57% | 80.83 | 328 / 578 | 3% | 0.09 | 32 / 1155 |
ovary | 1% | 0.43 | 1 / 180 | 44% | 2.16 | 188 / 430 |
blood vessel | 21% | 25.47 | 287 / 1335 | 0% | 0 | 0 / 0 |
breast | 7% | 9.37 | 33 / 459 | 11% | 0.40 | 121 / 1118 |
intestine | 14% | 14.79 | 132 / 966 | 4% | 0.18 | 19 / 527 |
lymph node | 0% | 0 | 0 / 0 | 17% | 0.46 | 5 / 29 |
stomach | 14% | 16.24 | 49 / 359 | 3% | 0.08 | 10 / 286 |
liver | 4% | 3.49 | 8 / 226 | 13% | 0.77 | 51 / 406 |
thymus | 9% | 9.06 | 59 / 653 | 6% | 0.09 | 34 / 605 |
uterus | 1% | 5.15 | 2 / 170 | 6% | 0.39 | 28 / 459 |
heart | 7% | 6.72 | 59 / 861 | 0% | 0 | 0 / 0 |
esophagus | 1% | 1.19 | 17 / 1445 | 4% | 0.20 | 7 / 183 |
prostate | 1% | 0.75 | 2 / 245 | 3% | 0.05 | 15 / 502 |
adipose | 3% | 3.87 | 40 / 1204 | 0% | 0 | 0 / 0 |
bladder | 0% | 0 | 0 / 21 | 2% | 0.06 | 11 / 504 |
spleen | 1% | 1.17 | 2 / 241 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0050804 | Biological process | modulation of chemical synaptic transmission |
GO_0001558 | Biological process | regulation of cell growth |
GO_0048513 | Biological process | animal organ development |
GO_0038138 | Biological process | ERBB4-ERBB4 signaling pathway |
GO_2001223 | Biological process | negative regulation of neuron migration |
GO_0060596 | Biological process | mammary placode formation |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0007416 | Biological process | synapse assembly |
GO_0021842 | Biological process | chemorepulsion involved in interneuron migration from the subpallium to the cortex |
GO_0007389 | Biological process | pattern specification process |
GO_0038130 | Biological process | ERBB4 signaling pathway |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0048018 | Molecular function | receptor ligand activity |
GO_0008083 | Molecular function | growth factor activity |
GO_0045499 | Molecular function | chemorepellent activity |
GO_0030297 | Molecular function | transmembrane receptor protein tyrosine kinase activator activity |
GO_0030971 | Molecular function | receptor tyrosine kinase binding |
Gene name | NRG3 |
Protein name | Neuregulin 3 variant 8 Neuregulin 3 (Neuregulin 3 variant 9) Neuregulin 3 variant 7 Neuregulin 3 variant 11 Neuregulin 3 variant 5 Neuregulin 3 variant 4 Neuregulin 3 variant 3 Pro-neuregulin-3, membrane-bound isoform (Pro-NRG3) [Cleaved into: Neuregulin-3 (NRG-3)] Neuregulin 3 variant 1 Neuregulin 3 variant 6 Neuregulin 3 |
Synonyms | |
Description | FUNCTION: Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes. . |
Accessions | D9ZHQ6 D9ZHP7 D9ZHP6 ENST00000556918.5 ENST00000372142.6 [P56975-3] ENST00000537893.1 ENST00000372141.7 [P56975-4] ENST00000404576.6 R4GNI6 D9ZHQ2 D9ZHQ1 D9ZHP9 B9EGV5 ENST00000602794.5 ENST00000404547.5 [P56975-1] D9ZHQ0 ENST00000545131.5 D9ZHQ3 D9ZHQ5 P56975 ENST00000555784.5 D9ZHP8 D9ZHQ8 D9ZHQ7 |