ERBB4-ERBB4 signaling pathway

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1BTC-ERBB4BTC_HUMAN - ERBB4_HUMANLigand-ReceptorSignaling by Betacellulin
2EREG-ERBB4EREG_HUMAN - ERBB4_HUMANLigand-ReceptorSignaling by Epidermal growth factor
3NRG1-ERBB4NRG1_HUMAN - ERBB4_HUMANLigand-ReceptorSignaling by Neuregulin
4NRG3-ERBB4NRG3_HUMAN - ERBB4_HUMANLigand-ReceptorSignaling by Neuregulin
5NRG4-ERBB4NRG4_HUMAN - ERBB4_HUMANLigand-ReceptorSignaling by Neuregulin

II. Literature review

[source]
NameERBB4-ERBB4 signaling pathway
IDGO_0038138
collection_id

Biological process

Exact synonym

ERBB4 homodimeric signaling pathway, ERBB4-ERBB4 signalling pathway, HER4-HER4 signaling pathway

Description

The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4, followed by ligand-induced homodimerization of ERBB4 and transmission of the signal into the cell by the homodimeric ERBB4 complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.

External URL
Genes