Interactors | Protein name | Directionality | Classification | |
---|---|---|---|---|
1 | BTC-ERBB4 | BTC_HUMAN - ERBB4_HUMAN | Ligand-Receptor | Signaling by Betacellulin |
2 | EREG-ERBB4 | EREG_HUMAN - ERBB4_HUMAN | Ligand-Receptor | Signaling by Epidermal growth factor |
3 | NRG1-ERBB4 | NRG1_HUMAN - ERBB4_HUMAN | Ligand-Receptor | Signaling by Neuregulin |
4 | NRG3-ERBB4 | NRG3_HUMAN - ERBB4_HUMAN | Ligand-Receptor | Signaling by Neuregulin |
5 | NRG4-ERBB4 | NRG4_HUMAN - ERBB4_HUMAN | Ligand-Receptor | Signaling by Neuregulin |
Name | ERBB4-ERBB4 signaling pathway |
ID | GO_0038138 |
collection_id | Biological process |
Exact synonym | ERBB4 homodimeric signaling pathway, ERBB4-ERBB4 signalling pathway, HER4-HER4 signaling pathway |
Description | The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4, followed by ligand-induced homodimerization of ERBB4 and transmission of the signal into the cell by the homodimeric ERBB4 complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription. |
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Genes |