BTC report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of BTC at tissue level.

III. Associated gene sets

GO_0051781Biological processpositive regulation of cell division
GO_0048146Biological processpositive regulation of fibroblast proliferation
GO_0008283Biological processcell population proliferation
GO_0038138Biological processERBB4-ERBB4 signaling pathway
GO_0045597Biological processpositive regulation of cell differentiation
GO_0038134Biological processERBB2-EGFR signaling pathway
GO_1904036Biological processnegative regulation of epithelial cell apoptotic process
GO_1904019Biological processepithelial cell apoptotic process
GO_0007173Biological processepidermal growth factor receptor signaling pathway
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0035810Biological processpositive regulation of urine volume
GO_0045840Biological processpositive regulation of mitotic nuclear division
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0030669Cellular componentclathrin-coated endocytic vesicle membrane
GO_0048018Molecular functionreceptor ligand activity
GO_0005154Molecular functionepidermal growth factor receptor binding
GO_0008083Molecular functiongrowth factor activity
GO_0030297Molecular functiontransmembrane receptor protein tyrosine kinase activator activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameBTC
Protein nameBetacellulin
Probetacellulin [Cleaved into: Betacellulin (BTC)]
Betacellulin isoform 2
SynonymshCG_24384
DescriptionFUNCTION: Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. .

AccessionsH0Y8Q5
P35070
ENST00000395743.8
ENST00000512743.1
A0A0S2Z437
A0A0S2Z3I5