Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 20 studies | 27% ± 10% | |
fibroblast | 15 studies | 22% ± 5% | |
epithelial cell | 12 studies | 35% ± 16% | |
pericyte | 10 studies | 21% ± 5% | |
glutamatergic neuron | 9 studies | 36% ± 24% | |
smooth muscle cell | 8 studies | 19% ± 2% | |
type I pneumocyte | 8 studies | 25% ± 5% | |
basal cell | 8 studies | 29% ± 13% | |
oligodendrocyte precursor cell | 8 studies | 27% ± 11% | |
ciliated cell | 7 studies | 29% ± 12% | |
secretory cell | 7 studies | 29% ± 11% | |
GABAergic neuron | 7 studies | 36% ± 18% | |
astrocyte | 7 studies | 29% ± 12% | |
goblet cell | 6 studies | 27% ± 13% | |
macrophage | 6 studies | 22% ± 3% | |
oligodendrocyte | 6 studies | 24% ± 7% | |
respiratory goblet cell | 5 studies | 23% ± 9% | |
neuron | 5 studies | 27% ± 8% | |
adipocyte | 5 studies | 20% ± 6% | |
myofibroblast cell | 5 studies | 22% ± 5% | |
endothelial cell of lymphatic vessel | 5 studies | 19% ± 3% | |
squamous epithelial cell | 4 studies | 46% ± 22% | |
microglial cell | 4 studies | 24% ± 3% | |
club cell | 4 studies | 31% ± 8% | |
abnormal cell | 4 studies | 35% ± 17% | |
connective tissue cell | 4 studies | 21% ± 4% | |
brush cell | 4 studies | 30% ± 14% | |
enterocyte | 4 studies | 18% ± 4% | |
interneuron | 4 studies | 41% ± 23% | |
granule cell | 3 studies | 19% ± 2% | |
progenitor cell | 3 studies | 17% ± 2% | |
retinal ganglion cell | 3 studies | 44% ± 22% | |
capillary endothelial cell | 3 studies | 17% ± 1% | |
retinal cone cell | 3 studies | 21% ± 1% | |
Mueller cell | 3 studies | 21% ± 0% | |
endothelial cell of vascular tree | 3 studies | 25% ± 1% | |
luminal hormone-sensing cell of mammary gland | 3 studies | 22% ± 4% | |
type II pneumocyte | 3 studies | 23% ± 3% | |
hepatocyte | 3 studies | 39% ± 13% | |
podocyte | 3 studies | 38% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4326.53 | 1445 / 1445 | 100% | 76.11 | 183 / 183 |
ovary | 100% | 5873.60 | 180 / 180 | 100% | 54.54 | 430 / 430 |
prostate | 100% | 3905.19 | 245 / 245 | 100% | 72.00 | 502 / 502 |
lung | 100% | 3871.03 | 577 / 578 | 100% | 64.12 | 1154 / 1155 |
breast | 100% | 4189.02 | 459 / 459 | 100% | 84.57 | 1114 / 1118 |
brain | 100% | 4301.62 | 2639 / 2642 | 100% | 84.88 | 703 / 705 |
kidney | 100% | 4945.31 | 89 / 89 | 99% | 82.31 | 896 / 901 |
intestine | 100% | 4696.79 | 966 / 966 | 99% | 66.23 | 524 / 527 |
uterus | 100% | 4504.15 | 170 / 170 | 99% | 53.16 | 456 / 459 |
stomach | 100% | 3092.35 | 359 / 359 | 99% | 70.55 | 284 / 286 |
pancreas | 100% | 1926.67 | 327 / 328 | 99% | 65.87 | 177 / 178 |
adrenal gland | 100% | 3674.53 | 258 / 258 | 99% | 55.48 | 228 / 230 |
liver | 100% | 2691.08 | 226 / 226 | 99% | 49.79 | 402 / 406 |
bladder | 100% | 4817.10 | 21 / 21 | 99% | 61.14 | 499 / 504 |
thymus | 100% | 4327.19 | 653 / 653 | 99% | 67.80 | 598 / 605 |
skin | 100% | 3490.11 | 1807 / 1809 | 97% | 74.78 | 456 / 472 |
adipose | 100% | 4460.40 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 6296.51 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 3130.45 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2091.42 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 31.27 | 1 / 1 |
tonsil | 0% | 0 | 0 / 0 | 98% | 43.19 | 44 / 45 |
heart | 96% | 2230.50 | 829 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 90% | 40.52 | 72 / 80 |
peripheral blood | 19% | 208.39 | 181 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 17% | 2.31 | 5 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_2000402 | Biological process | negative regulation of lymphocyte migration |
GO_0009617 | Biological process | response to bacterium |
GO_0032880 | Biological process | regulation of protein localization |
GO_0030041 | Biological process | actin filament polymerization |
GO_1903526 | Biological process | negative regulation of membrane tubulation |
GO_0051301 | Biological process | cell division |
GO_0030050 | Biological process | vesicle transport along actin filament |
GO_0008154 | Biological process | actin polymerization or depolymerization |
GO_0065003 | Biological process | protein-containing complex assembly |
GO_0051491 | Biological process | positive regulation of filopodium assembly |
GO_0051653 | Biological process | spindle localization |
GO_0016050 | Biological process | vesicle organization |
GO_0006900 | Biological process | vesicle budding from membrane |
GO_2000370 | Biological process | positive regulation of clathrin-dependent endocytosis |
GO_0031503 | Biological process | protein-containing complex localization |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0099175 | Biological process | regulation of postsynapse organization |
GO_0060997 | Biological process | dendritic spine morphogenesis |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0031410 | Cellular component | cytoplasmic vesicle |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0030478 | Cellular component | actin cap |
GO_0030666 | Cellular component | endocytic vesicle membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0030027 | Cellular component | lamellipodium |
GO_0005634 | Cellular component | nucleus |
GO_0003779 | Molecular function | actin binding |
GO_0030695 | Molecular function | GTPase regulator activity |
GO_0008017 | Molecular function | microtubule binding |
GO_0005515 | Molecular function | protein binding |
Gene name | WASL |
Protein name | Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP) Wiskott-Aldrich syndrome-like |
Synonyms | tcag7.28 |
Description | FUNCTION: Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex . Involved in various processes, such as mitosis and cytokinesis, via its role in the regulation of actin polymerization . Together with CDC42, involved in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia . In addition to its role in the cytoplasm, also plays a role in the nucleus by regulating gene transcription, probably by promoting nuclear actin polymerization . Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression (By similarity). Plays a role in dendrite spine morphogenesis (By similarity). Decreasing levels of DNMBP (using antisense RNA) alters apical junction morphology in cultured enterocytes, junctions curve instead of being nearly linear . . |
Accessions | O00401 ENST00000223023.5 A4D0Y1 |