Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 20 studies | 27% ± 10% | |
| fibroblast | 15 studies | 22% ± 5% | |
| epithelial cell | 12 studies | 35% ± 16% | |
| pericyte | 10 studies | 21% ± 5% | |
| glutamatergic neuron | 9 studies | 36% ± 24% | |
| smooth muscle cell | 8 studies | 19% ± 2% | |
| type I pneumocyte | 8 studies | 25% ± 5% | |
| basal cell | 8 studies | 29% ± 13% | |
| oligodendrocyte precursor cell | 8 studies | 27% ± 11% | |
| ciliated cell | 7 studies | 29% ± 12% | |
| secretory cell | 7 studies | 29% ± 11% | |
| GABAergic neuron | 7 studies | 36% ± 18% | |
| astrocyte | 7 studies | 29% ± 12% | |
| goblet cell | 6 studies | 27% ± 13% | |
| macrophage | 6 studies | 22% ± 3% | |
| oligodendrocyte | 6 studies | 24% ± 7% | |
| respiratory goblet cell | 5 studies | 23% ± 9% | |
| neuron | 5 studies | 27% ± 8% | |
| adipocyte | 5 studies | 20% ± 6% | |
| myofibroblast cell | 5 studies | 22% ± 5% | |
| endothelial cell of lymphatic vessel | 5 studies | 19% ± 3% | |
| squamous epithelial cell | 4 studies | 46% ± 22% | |
| microglial cell | 4 studies | 24% ± 3% | |
| club cell | 4 studies | 31% ± 8% | |
| abnormal cell | 4 studies | 35% ± 17% | |
| connective tissue cell | 4 studies | 21% ± 4% | |
| brush cell | 4 studies | 30% ± 14% | |
| enterocyte | 4 studies | 18% ± 4% | |
| interneuron | 4 studies | 41% ± 23% | |
| granule cell | 3 studies | 19% ± 2% | |
| progenitor cell | 3 studies | 17% ± 2% | |
| retinal ganglion cell | 3 studies | 44% ± 22% | |
| capillary endothelial cell | 3 studies | 17% ± 1% | |
| retinal cone cell | 3 studies | 21% ± 1% | |
| Mueller cell | 3 studies | 21% ± 0% | |
| endothelial cell of vascular tree | 3 studies | 25% ± 1% | |
| luminal hormone-sensing cell of mammary gland | 3 studies | 22% ± 4% | |
| type II pneumocyte | 3 studies | 23% ± 3% | |
| hepatocyte | 3 studies | 39% ± 13% | |
| podocyte | 3 studies | 38% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 4326.53 | 1445 / 1445 | 100% | 76.11 | 183 / 183 |
| ovary | 100% | 5873.60 | 180 / 180 | 100% | 54.54 | 430 / 430 |
| prostate | 100% | 3905.19 | 245 / 245 | 100% | 72.00 | 502 / 502 |
| lung | 100% | 3871.03 | 577 / 578 | 100% | 64.12 | 1154 / 1155 |
| breast | 100% | 4189.02 | 459 / 459 | 100% | 84.57 | 1114 / 1118 |
| brain | 100% | 4301.62 | 2639 / 2642 | 100% | 84.88 | 703 / 705 |
| kidney | 100% | 4945.31 | 89 / 89 | 99% | 82.31 | 896 / 901 |
| intestine | 100% | 4696.79 | 966 / 966 | 99% | 66.23 | 524 / 527 |
| uterus | 100% | 4504.15 | 170 / 170 | 99% | 53.16 | 456 / 459 |
| stomach | 100% | 3092.35 | 359 / 359 | 99% | 70.55 | 284 / 286 |
| pancreas | 100% | 1926.67 | 327 / 328 | 99% | 65.87 | 177 / 178 |
| adrenal gland | 100% | 3674.53 | 258 / 258 | 99% | 55.48 | 228 / 230 |
| liver | 100% | 2691.08 | 226 / 226 | 99% | 49.79 | 402 / 406 |
| bladder | 100% | 4817.10 | 21 / 21 | 99% | 61.14 | 499 / 504 |
| thymus | 100% | 4327.19 | 653 / 653 | 99% | 67.80 | 598 / 605 |
| skin | 100% | 3490.11 | 1807 / 1809 | 97% | 74.78 | 456 / 472 |
| adipose | 100% | 4460.40 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 6296.51 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 3130.45 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2091.42 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 31.27 | 1 / 1 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 43.19 | 44 / 45 |
| heart | 96% | 2230.50 | 829 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 90% | 40.52 | 72 / 80 |
| peripheral blood | 19% | 208.39 | 181 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 17% | 2.31 | 5 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_2000402 | Biological process | negative regulation of lymphocyte migration |
| GO_0009617 | Biological process | response to bacterium |
| GO_0032880 | Biological process | regulation of protein localization |
| GO_0030041 | Biological process | actin filament polymerization |
| GO_1903526 | Biological process | negative regulation of membrane tubulation |
| GO_0051301 | Biological process | cell division |
| GO_0030050 | Biological process | vesicle transport along actin filament |
| GO_0008154 | Biological process | actin polymerization or depolymerization |
| GO_0065003 | Biological process | protein-containing complex assembly |
| GO_0051491 | Biological process | positive regulation of filopodium assembly |
| GO_0051653 | Biological process | spindle localization |
| GO_0016050 | Biological process | vesicle organization |
| GO_0006900 | Biological process | vesicle budding from membrane |
| GO_2000370 | Biological process | positive regulation of clathrin-dependent endocytosis |
| GO_0031503 | Biological process | protein-containing complex localization |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0099175 | Biological process | regulation of postsynapse organization |
| GO_0060997 | Biological process | dendritic spine morphogenesis |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0031410 | Cellular component | cytoplasmic vesicle |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0030478 | Cellular component | actin cap |
| GO_0030666 | Cellular component | endocytic vesicle membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0015629 | Cellular component | actin cytoskeleton |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0030027 | Cellular component | lamellipodium |
| GO_0005634 | Cellular component | nucleus |
| GO_0003779 | Molecular function | actin binding |
| GO_0030695 | Molecular function | GTPase regulator activity |
| GO_0008017 | Molecular function | microtubule binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | WASL |
| Protein name | Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP) Wiskott-Aldrich syndrome-like |
| Synonyms | tcag7.28 |
| Description | FUNCTION: Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex . Involved in various processes, such as mitosis and cytokinesis, via its role in the regulation of actin polymerization . Together with CDC42, involved in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia . In addition to its role in the cytoplasm, also plays a role in the nucleus by regulating gene transcription, probably by promoting nuclear actin polymerization . Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression (By similarity). Plays a role in dendrite spine morphogenesis (By similarity). Decreasing levels of DNMBP (using antisense RNA) alters apical junction morphology in cultured enterocytes, junctions curve instead of being nearly linear . . |
| Accessions | O00401 ENST00000223023.5 A4D0Y1 |