P2RY4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of P2RY4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of P2RY4 at tissue level.

III. Associated gene sets

GO_0071380Biological processcellular response to prostaglandin E stimulus
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0071318Biological processcellular response to ATP
GO_0007204Biological processpositive regulation of cytosolic calcium ion concentration
GO_0007200Biological processphospholipase C-activating G protein-coupled receptor signaling pathway
GO_0035589Biological processG protein-coupled purinergic nucleotide receptor signaling pathway
GO_0030321Biological processtransepithelial chloride transport
GO_2000300Biological processregulation of synaptic vesicle exocytosis
GO_0099509Biological processregulation of presynaptic cytosolic calcium ion concentration
GO_0016323Cellular componentbasolateral plasma membrane
GO_0016324Cellular componentapical plasma membrane
GO_0098978Cellular componentglutamatergic synapse
GO_0048787Cellular componentpresynaptic active zone membrane
GO_0005886Cellular componentplasma membrane
GO_0045030Molecular functionG protein-coupled UTP receptor activity
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding
GO_0045028Molecular functionG protein-coupled purinergic nucleotide receptor activity

IV. Literature review

[source]
Gene nameP2RY4
Protein nameP2Y purinoceptor 4
P2Y purinoceptor 4 (P2Y4) (P2P) (Uridine nucleotide receptor) (UNR)
SynonymsNRU
DescriptionFUNCTION: Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP.

AccessionsC6G7W4
P51582
C6G7W3
ENST00000374519.4