STK38 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	23 studies	25% ± 7%	Explore
endothelial cell	15 studies	29% ± 12%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	29% ± 7%	Explore
CD4-positive, alpha-beta T cell	14 studies	24% ± 5%	Explore
non-classical monocyte	12 studies	25% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	26% ± 8%	Explore
T cell	11 studies	23% ± 8%	Explore
ciliated cell	11 studies	23% ± 9%	Explore
classical monocyte	11 studies	23% ± 7%	Explore
basal cell	10 studies	32% ± 15%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	22% ± 4%	Explore
CD8-positive, alpha-beta T cell	10 studies	26% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	21% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	23% ± 6%	Explore
mature NK T cell	9 studies	22% ± 4%	Explore
mucosal invariant T cell	9 studies	24% ± 6%	Explore
regulatory T cell	9 studies	26% ± 7%	Explore
macrophage	8 studies	30% ± 9%	Explore
monocyte	8 studies	27% ± 12%	Explore
gamma-delta T cell	8 studies	24% ± 4%	Explore
club cell	7 studies	28% ± 10%	Explore
epithelial cell	7 studies	32% ± 17%	Explore
astrocyte	7 studies	25% ± 8%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	20% ± 3%	Explore
respiratory goblet cell	6 studies	36% ± 12%	Explore
dendritic cell	6 studies	24% ± 4%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	22% ± 8%	Explore
microglial cell	5 studies	30% ± 12%	Explore
myeloid cell	5 studies	21% ± 3%	Explore
B cell	5 studies	25% ± 9%	Explore
GABAergic neuron	5 studies	37% ± 11%	Explore
glutamatergic neuron	5 studies	54% ± 9%	Explore
fibroblast	5 studies	27% ± 13%	Explore
type I pneumocyte	5 studies	26% ± 7%	Explore
interneuron	5 studies	41% ± 23%	Explore
oligodendrocyte	5 studies	24% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	27% ± 7%	Explore
squamous epithelial cell	4 studies	39% ± 19%	Explore
cardiac muscle cell	4 studies	18% ± 1%	Explore
oligodendrocyte precursor cell	4 studies	29% ± 7%	Explore
brush cell	4 studies	38% ± 14%	Explore
endothelial cell of lymphatic vessel	4 studies	19% ± 4%	Explore
pericyte	4 studies	24% ± 10%	Explore
secretory cell	3 studies	32% ± 2%	Explore
leukocyte	3 studies	25% ± 13%	Explore
neuron	3 studies	33% ± 8%	Explore
precursor B cell	3 studies	26% ± 3%	Explore
immature B cell	3 studies	23% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	25% ± 0%	Explore
alveolar macrophage	3 studies	25% ± 8%	Explore
lymphocyte	3 studies	44% ± 9%	Explore
goblet cell	3 studies	38% ± 31%	Explore
plasmacytoid dendritic cell	3 studies	18% ± 3%	Explore
double negative thymocyte	3 studies	24% ± 4%	Explore
mural cell	3 studies	36% ± 19%	Explore
mucus secreting cell	3 studies	27% ± 14%	Explore
innate lymphoid cell	3 studies	33% ± 9%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	11 studies	24% ± 5%	Explore
brain	7 studies	39% ± 14%	Explore
lung	6 studies	22% ± 7%	Explore
adipose	4 studies	25% ± 3%	Explore
heart	3 studies	18% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	5250.43	21 / 21	100%	82.15	504 / 504
breast	100%	4415.19	459 / 459	100%	69.84	1118 / 1118
esophagus	100%	5412.23	1445 / 1445	100%	80.40	183 / 183
intestine	100%	6546.73	966 / 966	100%	88.91	527 / 527
prostate	100%	4467.59	245 / 245	100%	37.54	502 / 502
uterus	100%	4208.45	170 / 170	100%	89.56	459 / 459
lung	100%	4530.53	577 / 578	100%	74.48	1154 / 1155
ovary	100%	2724.71	180 / 180	99%	47.64	427 / 430
skin	100%	4846.32	1809 / 1809	99%	50.22	467 / 472
stomach	99%	2745.65	355 / 359	100%	83.29	285 / 286
thymus	100%	2721.06	653 / 653	98%	35.33	591 / 605
kidney	100%	3471.46	89 / 89	95%	45.55	858 / 901
liver	100%	2278.16	226 / 226	94%	32.84	380 / 406
brain	94%	1596.59	2481 / 2642	98%	31.95	689 / 705
pancreas	87%	1211.96	284 / 328	98%	73.66	175 / 178
adrenal gland	99%	1962.31	256 / 258	84%	17.12	193 / 230
adipose	100%	4830.37	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	55.63	29 / 29
spleen	100%	6085.83	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	86.28	45 / 45
ureter	0%	0	0 / 0	100%	118.55	1 / 1
blood vessel	99%	2560.49	1328 / 1335	0%	0	0 / 0
peripheral blood	99%	7667.55	924 / 929	0%	0	0 / 0
heart	99%	2590.64	850 / 861	0%	0	0 / 0
muscle	97%	1654.66	779 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	85%	24.38	68 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006325	Biological process	chromatin organization
GO_0018105	Biological process	peptidyl-serine phosphorylation
GO_0099173	Biological process	postsynapse organization
GO_0006974	Biological process	DNA damage response
GO_0035556	Biological process	intracellular signal transduction
GO_0036211	Biological process	protein modification process
GO_0043407	Biological process	negative regulation of MAP kinase activity
GO_0006468	Biological process	protein phosphorylation
GO_0000077	Biological process	DNA damage checkpoint signaling
GO_0098978	Cellular component	glutamatergic synapse
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0035861	Cellular component	site of double-strand break
GO_0005634	Cellular component	nucleus
GO_0106310	Molecular function	protein serine kinase activity
GO_0045296	Molecular function	cadherin binding
GO_0031435	Molecular function	mitogen-activated protein kinase kinase kinase binding
GO_0141185	Molecular function	UFM1-modified protein reader activity
GO_0004674	Molecular function	protein serine/threonine kinase activity
GO_0000287	Molecular function	magnesium ion binding
GO_0140566	Molecular function	histone reader activity
GO_0005524	Molecular function	ATP binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	STK38
Protein name	Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)
Synonyms	NDR1
Description	FUNCTION: Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2. .
Accessions	Q15208 ENST00000229812.8

STK38 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review