DNM3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0099173Biological processpostsynapse organization
GO_0031623Biological processreceptor internalization
GO_1903423Biological processpositive regulation of synaptic vesicle recycling
GO_0006897Biological processendocytosis
GO_0098884Biological processpostsynaptic neurotransmitter receptor internalization
GO_0061002Biological processnegative regulation of dendritic spine morphogenesis
GO_0016185Biological processsynaptic vesicle budding from presynaptic endocytic zone membrane
GO_0051491Biological processpositive regulation of filopodium assembly
GO_0046847Biological processfilopodium assembly
GO_0007416Biological processsynapse assembly
GO_0098978Cellular componentglutamatergic synapse
GO_0098793Cellular componentpresynapse
GO_0005886Cellular componentplasma membrane
GO_0005874Cellular componentmicrotubule
GO_0043197Cellular componentdendritic spine
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0070062Cellular componentextracellular exosome
GO_0061828Cellular componentapical tubulobulbar complex
GO_0045202Cellular componentsynapse
GO_0014069Cellular componentpostsynaptic density
GO_0005737Cellular componentcytoplasm
GO_0044327Cellular componentdendritic spine head
GO_0043083Cellular componentsynaptic cleft
GO_0030424Cellular componentaxon
GO_0061829Cellular componentbasal tubulobulbar complex
GO_0098844Cellular componentpostsynaptic endocytic zone membrane
GO_0050998Molecular functionnitric-oxide synthase binding
GO_0099186Molecular functionstructural constituent of postsynapse
GO_0005525Molecular functionGTP binding
GO_0120283Molecular functionprotein serine/threonine kinase binding
GO_0008017Molecular functionmicrotubule binding
GO_0031798Molecular functiontype 1 metabotropic glutamate receptor binding
GO_0005515Molecular functionprotein binding
GO_0031802Molecular functiontype 5 metabotropic glutamate receptor binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameDNM3
Protein namedynamin GTPase (EC 3.6.5.5)
Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)
SynonymsKIAA0820
DescriptionFUNCTION: Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity). .

AccessionsENST00000688173.1
ENST00000355305.9 [Q9UQ16-1]
ENST00000367733.6 [Q9UQ16-5]
Q9UQ16
ENST00000627582.3 [Q9UQ16-3]
ENST00000520906.5
A0A8I5KXV5
E5RIK2
ENST00000523513.1
ENST00000485254.3
ENST00000367731.5 [Q9UQ16-2]
E5RHK8
H0YBC6