DOC2A | OmnibusX

Name	Number of supported studies	Average coverage
ciliated cell	11 studies	34% ± 15%	Explore
glutamatergic neuron	5 studies	32% ± 19%	Explore

Name	Number of supported studies	Average coverage
brain	3 studies	26% ± 15%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	91%	3279.96	2405 / 2642	81%	6.45	573 / 705
kidney	73%	355.08	65 / 89	79%	12.92	712 / 901
ovary	92%	1293.93	165 / 180	40%	1.26	172 / 430
prostate	82%	730.30	200 / 245	28%	0.65	140 / 502
adrenal gland	62%	311.56	161 / 258	39%	1.22	90 / 230
breast	32%	150.77	147 / 459	58%	2.27	645 / 1118
lung	52%	490.14	303 / 578	31%	1.05	354 / 1155
spleen	81%	476.61	195 / 241	0%	0	0 / 0
intestine	47%	341.85	458 / 966	30%	0.99	158 / 527
uterus	36%	168.04	61 / 170	29%	0.93	133 / 459
esophagus	16%	57.46	231 / 1445	34%	0.91	63 / 183
stomach	3%	9.96	11 / 359	33%	1.02	94 / 286
bladder	5%	9.86	1 / 21	25%	0.85	126 / 504
pancreas	8%	23.69	26 / 328	19%	0.68	33 / 178
tonsil	0%	0	0 / 0	22%	0.74	10 / 45
adipose	19%	84.83	233 / 1204	0%	0	0 / 0
thymus	8%	27.76	49 / 653	3%	0.08	19 / 605
skin	1%	3.26	20 / 1809	7%	0.15	35 / 472
liver	0%	0.91	1 / 226	6%	0.18	25 / 406
blood vessel	2%	6.59	29 / 1335	0%	0	0 / 0
heart	2%	6.01	17 / 861	0%	0	0 / 0
muscle	0%	0.33	1 / 803	0%	0	0 / 0
peripheral blood	0%	0.51	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0017158	Biological process	regulation of calcium ion-dependent exocytosis
GO_0007399	Biological process	nervous system development
GO_0006887	Biological process	exocytosis
GO_0099502	Biological process	calcium-dependent activation of synaptic vesicle fusion
GO_0007268	Biological process	chemical synaptic transmission
GO_0061669	Biological process	spontaneous neurotransmitter secretion
GO_0005730	Cellular component	nucleolus
GO_0030054	Cellular component	cell junction
GO_0098978	Cellular component	glutamatergic synapse
GO_0005764	Cellular component	lysosome
GO_0005654	Cellular component	nucleoplasm
GO_0045202	Cellular component	synapse
GO_0098850	Cellular component	extrinsic component of synaptic vesicle membrane
GO_0043005	Cellular component	neuron projection
GO_0005515	Molecular function	protein binding
GO_0005544	Molecular function	calcium-dependent phospholipid binding
GO_0046872	Molecular function	metal ion binding

Gene name	DOC2A
Protein name	Double C2 domain alpha Double C2-like domain-containing protein alpha (Doc2) (Doc2-alpha)
Synonyms
Description	FUNCTION: Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells. .
Accessions	H3BNF7 ENST00000616445.4 [Q14183-1] ENST00000564944.5 [Q14183-1] I3L194 H3BU41 ENST00000563125.5 Q14183 ENST00000566310.5 [Q14183-2] ENST00000563378.5 ENST00000565273.5 ENST00000567332.6 I3L3P9 ENST00000561671.5 ENST00000574405.5 H3BSH4 H3BTI1 ENST00000564979.5 [Q14183-1] ENST00000350119.9 [Q14183-1]

DOC2A report