ITPKA | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of ITPKA at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	85%	2277.95	2245 / 2642	93%	16.43	659 / 705
stomach	74%	721.06	266 / 359	94%	20.02	268 / 286
adrenal gland	98%	634.57	253 / 258	48%	8.55	111 / 230
intestine	48%	591.60	466 / 966	94%	20.50	493 / 527
pancreas	13%	22.90	42 / 328	76%	14.53	136 / 178
esophagus	3%	5.35	41 / 1445	81%	12.41	149 / 183
liver	14%	54.08	31 / 226	70%	11.74	284 / 406
tonsil	0%	0	0 / 0	78%	7.99	35 / 45
uterus	8%	14.05	13 / 170	64%	7.45	292 / 459
lung	5%	10.59	29 / 578	66%	14.94	759 / 1155
bladder	5%	6.48	1 / 21	43%	9.02	217 / 504
skin	14%	39.55	246 / 1809	29%	2.84	135 / 472
muscle	33%	228.93	266 / 803	0%	0	0 / 0
kidney	1%	1.90	1 / 89	26%	3.06	231 / 901
breast	0%	2.32	2 / 459	23%	1.83	253 / 1118
heart	20%	52.12	174 / 861	0%	0	0 / 0
ovary	1%	0.79	1 / 180	18%	1.10	79 / 430
thymus	0%	1.22	2 / 653	17%	0.93	101 / 605
prostate	13%	27.18	33 / 245	2%	0.09	9 / 502
peripheral blood	10%	23.52	97 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	3%	0.25	1 / 29
eye	0%	0	0 / 0	1%	0.04	1 / 80
adipose	1%	1.67	8 / 1204	0%	0	0 / 0
spleen	0%	0.61	1 / 241	0%	0	0 / 0
blood vessel	0%	0.46	2 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0061003	Biological process	positive regulation of dendritic spine morphogenesis
GO_0032958	Biological process	inositol phosphate biosynthetic process
GO_0007165	Biological process	signal transduction
GO_0046854	Biological process	phosphatidylinositol phosphate biosynthetic process
GO_0071277	Biological process	cellular response to calcium ion
GO_0030036	Biological process	actin cytoskeleton organization
GO_0048167	Biological process	regulation of synaptic plasticity
GO_0098885	Biological process	modification of postsynaptic actin cytoskeleton
GO_0097062	Biological process	dendritic spine maintenance
GO_0006020	Biological process	inositol metabolic process
GO_0051592	Biological process	response to calcium ion
GO_0098978	Cellular component	glutamatergic synapse
GO_0005856	Cellular component	cytoskeleton
GO_0043197	Cellular component	dendritic spine
GO_0005829	Cellular component	cytosol
GO_0098871	Cellular component	postsynaptic actin cytoskeleton
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0051765	Molecular function	inositol tetrakisphosphate kinase activity
GO_0008440	Molecular function	inositol-1,4,5-trisphosphate 3-kinase activity
GO_0031267	Molecular function	small GTPase binding
GO_0005524	Molecular function	ATP binding
GO_0004683	Molecular function	calmodulin-dependent protein kinase activity
GO_0005516	Molecular function	calmodulin binding

Gene name	ITPKA
Protein name	Kinase (EC 2.7.-.-) Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase A) (IP3 3-kinase A) (IP3K A) (InsP 3-kinase A)
Synonyms
Description	FUNCTION: Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis. .
Accessions	ENST00000260386.7 ENST00000425927.5 C9JC74 P23677

ITPKA report