SYT10 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SYT10 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SYT10 at tissue level.

III. Associated gene sets

GO_0017156Biological processcalcium-ion regulated exocytosis
GO_0045956Biological processpositive regulation of calcium ion-dependent exocytosis
GO_0007608Biological processsensory perception of smell
GO_0007268Biological processchemical synaptic transmission
GO_0016079Biological processsynaptic vesicle exocytosis
GO_0070382Cellular componentexocytic vesicle
GO_0098978Cellular componentglutamatergic synapse
GO_0098793Cellular componentpresynapse
GO_0030658Cellular componenttransport vesicle membrane
GO_0005886Cellular componentplasma membrane
GO_0030276Molecular functionclathrin binding
GO_0046982Molecular functionprotein heterodimerization activity
GO_0042803Molecular functionprotein homodimerization activity
GO_0000149Molecular functionSNARE binding
GO_0005546Molecular functionphosphatidylinositol-4,5-bisphosphate binding
GO_0005509Molecular functioncalcium ion binding
GO_0001786Molecular functionphosphatidylserine binding
GO_0005544Molecular functioncalcium-dependent phospholipid binding

IV. Literature review

[source]
Gene nameSYT10
Protein nameSYT10 protein
Synaptotagmin-10 (Synaptotagmin X) (SytX)
Synaptotagmin 10
Synonyms
DescriptionFUNCTION: Ca(2+) sensor specifically required for the Ca(2+)-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. Not involved in Ca(2+)-dependent synaptic vesicle exocytosis (By similarity). Acts through Ca(2+) and phospholipid binding to the C2 domain: Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis (By similarity). .

AccessionsF5GZB8
ENST00000539102.1
Q495U1
Q6XYQ8
ENST00000228567.7