Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 18 studies | 31% ± 13% | |
pericyte | 18 studies | 25% ± 13% | |
smooth muscle cell | 17 studies | 27% ± 11% | |
endothelial cell of lymphatic vessel | 14 studies | 36% ± 15% | |
macrophage | 14 studies | 27% ± 12% | |
microglial cell | 11 studies | 38% ± 14% | |
fibroblast | 10 studies | 22% ± 6% | |
mast cell | 10 studies | 24% ± 6% | |
type I pneumocyte | 9 studies | 38% ± 14% | |
ciliated cell | 9 studies | 26% ± 10% | |
myeloid cell | 8 studies | 33% ± 12% | |
epithelial cell | 8 studies | 31% ± 10% | |
GABAergic neuron | 7 studies | 34% ± 19% | |
oligodendrocyte precursor cell | 7 studies | 27% ± 9% | |
dendritic cell | 7 studies | 31% ± 8% | |
type II pneumocyte | 7 studies | 42% ± 14% | |
astrocyte | 7 studies | 26% ± 9% | |
retinal cone cell | 6 studies | 24% ± 6% | |
monocyte | 6 studies | 30% ± 10% | |
conventional dendritic cell | 5 studies | 25% ± 10% | |
non-classical monocyte | 5 studies | 21% ± 5% | |
lymphocyte | 5 studies | 20% ± 4% | |
glutamatergic neuron | 5 studies | 41% ± 20% | |
goblet cell | 5 studies | 33% ± 21% | |
club cell | 5 studies | 32% ± 7% | |
basal cell | 5 studies | 30% ± 12% | |
neuron | 5 studies | 30% ± 14% | |
classical monocyte | 4 studies | 22% ± 4% | |
myofibroblast cell | 4 studies | 27% ± 7% | |
platelet | 4 studies | 19% ± 3% | |
cardiac muscle cell | 4 studies | 20% ± 2% | |
interneuron | 4 studies | 40% ± 21% | |
squamous epithelial cell | 3 studies | 34% ± 18% | |
mononuclear phagocyte | 3 studies | 28% ± 9% | |
retinal rod cell | 3 studies | 27% ± 6% | |
endothelial cell of vascular tree | 3 studies | 28% ± 12% | |
cholangiocyte | 3 studies | 43% ± 21% | |
hepatocyte | 3 studies | 40% ± 31% | |
muscle cell | 3 studies | 35% ± 16% | |
respiratory goblet cell | 3 studies | 28% ± 8% | |
alveolar macrophage | 3 studies | 33% ± 8% | |
mesothelial cell | 3 studies | 24% ± 6% | |
oligodendrocyte | 3 studies | 23% ± 8% | |
mucus secreting cell | 3 studies | 26% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 6964.65 | 1445 / 1445 | 100% | 58.37 | 183 / 183 |
pancreas | 100% | 13256.03 | 328 / 328 | 100% | 98.33 | 178 / 178 |
prostate | 100% | 7646.33 | 245 / 245 | 100% | 100.98 | 502 / 502 |
skin | 100% | 5718.10 | 1809 / 1809 | 100% | 186.18 | 472 / 472 |
kidney | 100% | 6126.21 | 89 / 89 | 100% | 89.52 | 900 / 901 |
lung | 100% | 8127.69 | 578 / 578 | 100% | 78.19 | 1153 / 1155 |
uterus | 100% | 5707.48 | 170 / 170 | 100% | 60.33 | 458 / 459 |
breast | 100% | 6325.80 | 459 / 459 | 100% | 73.94 | 1115 / 1118 |
thymus | 100% | 7362.32 | 653 / 653 | 100% | 81.55 | 603 / 605 |
stomach | 100% | 6013.76 | 359 / 359 | 100% | 62.22 | 285 / 286 |
intestine | 100% | 7907.44 | 966 / 966 | 99% | 66.69 | 524 / 527 |
bladder | 100% | 5733.00 | 21 / 21 | 99% | 53.82 | 499 / 504 |
liver | 100% | 3383.40 | 225 / 226 | 98% | 61.21 | 399 / 406 |
brain | 98% | 3356.89 | 2584 / 2642 | 100% | 63.29 | 704 / 705 |
ovary | 100% | 4632.45 | 180 / 180 | 97% | 34.21 | 415 / 430 |
adrenal gland | 100% | 10546.55 | 258 / 258 | 95% | 47.40 | 219 / 230 |
blood vessel | 100% | 13381.88 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 61.71 | 29 / 29 |
spleen | 100% | 5562.25 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 59.69 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 37.80 | 1 / 1 |
adipose | 100% | 5774.38 | 1203 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 4354.81 | 799 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 4923.40 | 853 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 9068.98 | 918 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 127.76 | 79 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0050804 | Biological process | modulation of chemical synaptic transmission |
GO_0048858 | Biological process | cell projection morphogenesis |
GO_0072584 | Biological process | caveolin-mediated endocytosis |
GO_0045806 | Biological process | negative regulation of endocytosis |
GO_0007010 | Biological process | cytoskeleton organization |
GO_0097320 | Biological process | plasma membrane tubulation |
GO_0070836 | Biological process | caveola assembly |
GO_0030036 | Biological process | actin cytoskeleton organization |
GO_0030100 | Biological process | regulation of endocytosis |
GO_0036010 | Biological process | protein localization to endosome |
GO_0032587 | Cellular component | ruffle membrane |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0034451 | Cellular component | centriolar satellite |
GO_0005769 | Cellular component | early endosome |
GO_0016607 | Cellular component | nuclear speck |
GO_0070062 | Cellular component | extracellular exosome |
GO_0055038 | Cellular component | recycling endosome membrane |
GO_0005925 | Cellular component | focal adhesion |
GO_0005911 | Cellular component | cell-cell junction |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0005768 | Cellular component | endosome |
GO_0005901 | Cellular component | caveola |
GO_0005543 | Molecular function | phospholipid binding |
GO_0045296 | Molecular function | cadherin binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0070300 | Molecular function | phosphatidic acid binding |
GO_0008092 | Molecular function | cytoskeletal protein binding |
GO_0005515 | Molecular function | protein binding |
Gene name | PACSIN2 |
Protein name | PACSIN2 protein Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II) (SdpII) Protein kinase C and casein kinase substrate in neurons 2 |
Synonyms | |
Description | FUNCTION: Regulates the morphogenesis and endocytosis of caveolae (By similarity). Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. .; FUNCTION: (Microbial infection) Specifically enhances the efficiency of HIV-1 virion spread by cell-to-cell transfer . Also promotes the protrusion engulfment during cell-to-cell spread of bacterial pathogens like Listeria monocytogenes . Involved in lipid droplet formation, which is important for HCV virion assembly . . |
Accessions | ENST00000337959.8 [Q9UNF0-2] ENST00000453643.5 ENST00000634914.1 ENST00000402229.5 [Q9UNF0-1] ENST00000403744.7 [Q9UNF0-1] H0Y923 A0A0U1RR22 B0QYG9 B0QYG7 ENST00000453079.1 ENST00000407585.5 [Q9UNF0-2] ENST00000507586.1 ENST00000422336.5 Q9UNF0 ENST00000418133.5 Q6FIA3 B0QYG8 ENST00000263246.8 [Q9UNF0-1] |