CDKL5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0050804Biological processmodulation of chemical synaptic transmission
GO_0045773Biological processpositive regulation of axon extension
GO_0043547Biological processpositive regulation of GTPase activity
GO_0001764Biological processneuron migration
GO_1902017Biological processregulation of cilium assembly
GO_0050773Biological processregulation of dendrite development
GO_0050775Biological processpositive regulation of dendrite morphogenesis
GO_0060999Biological processpositive regulation of dendritic spine development
GO_0006468Biological processprotein phosphorylation
GO_0046777Biological processprotein autophosphorylation
GO_0051726Biological processregulation of cell cycle
GO_0099175Biological processregulation of postsynapse organization
GO_0032587Cellular componentruffle membrane
GO_0098978Cellular componentglutamatergic synapse
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005813Cellular componentcentrosome
GO_0005654Cellular componentnucleoplasm
GO_0097542Cellular componentciliary tip
GO_0044294Cellular componentdendritic growth cone
GO_0036064Cellular componentciliary basal body
GO_0032839Cellular componentdendrite cytoplasm
GO_0099092Cellular componentpostsynaptic density, intracellular component
GO_0005634Cellular componentnucleus
GO_0106310Molecular functionprotein serine kinase activity
GO_0004674Molecular functionprotein serine/threonine kinase activity
GO_0031267Molecular functionsmall GTPase binding
GO_0004672Molecular functionprotein kinase activity
GO_0005524Molecular functionATP binding
GO_0016301Molecular functionkinase activity
GO_0005515Molecular functionprotein binding
GO_0004693Molecular functioncyclin-dependent protein serine/threonine kinase activity

IV. Literature review

[source]
Gene nameCDKL5
Protein nameCyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)
Cyclin dependent kinase like 5
SynonymsSTK9
DescriptionFUNCTION: Mediates phosphorylation of MECP2 . May regulate ciliogenesis . .

AccessionsO76039
A0A1B0GTX4
ENST00000379989.6 [O76039-1]
ENST00000674046.1
ENST00000623364.3
A0A669KBC2
ENST00000623535.2 [O76039-2]
A0A096LNR9
A0A1B0GUM4
ENST00000637881.1
A0A096LPI4
ENST00000635828.1
A0A096LPG3
ENST00000463994.4
ENST00000624953.1
ENST00000624700.3
ENST00000379996.7 [O76039-1]
A0A096LP32