PRR7 | OmnibusX

Name	Number of supported studies	Average coverage
ciliated cell	6 studies	31% ± 7%	Explore
naive B cell	3 studies	21% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	21% ± 2%	Explore
gamma-delta T cell	3 studies	20% ± 2%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of PRR7 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	906.24	2635 / 2642	94%	14.65	661 / 705
skin	98%	377.25	1767 / 1809	94%	19.87	442 / 472
adrenal gland	94%	212.17	243 / 258	88%	16.58	202 / 230
esophagus	53%	86.59	770 / 1445	100%	32.15	183 / 183
pancreas	63%	80.44	208 / 328	76%	8.20	135 / 178
uterus	61%	88.28	103 / 170	76%	10.67	349 / 459
intestine	43%	53.68	416 / 966	93%	23.20	492 / 527
prostate	68%	97.95	167 / 245	68%	6.60	341 / 502
lung	68%	108.31	391 / 578	68%	8.31	784 / 1155
stomach	33%	35.43	117 / 359	98%	24.49	280 / 286
breast	58%	84.63	267 / 459	65%	6.81	722 / 1118
kidney	62%	121.27	55 / 89	56%	5.15	503 / 901
ovary	12%	12.67	21 / 180	100%	53.97	428 / 430
bladder	29%	29.05	6 / 21	77%	12.07	390 / 504
thymus	55%	63.47	358 / 653	49%	4.15	295 / 605
ureter	0%	0	0 / 0	100%	5.50	1 / 1
lymph node	0%	0	0 / 0	97%	11.41	28 / 29
peripheral blood	96%	388.79	894 / 929	0%	0	0 / 0
spleen	96%	182.18	231 / 241	0%	0	0 / 0
eye	0%	0	0 / 0	94%	14.90	75 / 80
liver	31%	52.57	69 / 226	46%	4.47	185 / 406
tonsil	0%	0	0 / 0	60%	5.09	27 / 45
blood vessel	36%	42.25	487 / 1335	0%	0	0 / 0
adipose	32%	38.25	391 / 1204	0%	0	0 / 0
heart	18%	20.45	156 / 861	0%	0	0 / 0
muscle	15%	17.32	124 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0033077	Biological process	T cell differentiation in thymus
GO_0002250	Biological process	adaptive immune response
GO_2001269	Biological process	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO_0099527	Biological process	postsynapse to nucleus signaling pathway
GO_0046632	Biological process	alpha-beta T cell differentiation
GO_0043065	Biological process	positive regulation of apoptotic process
GO_0006356	Biological process	regulation of transcription by RNA polymerase I
GO_0098978	Cellular component	glutamatergic synapse
GO_0098839	Cellular component	postsynaptic density membrane
GO_0005886	Cellular component	plasma membrane
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005654	Cellular component	nucleoplasm
GO_0030425	Cellular component	dendrite
GO_0005829	Cellular component	cytosol
GO_0099092	Cellular component	postsynaptic density, intracellular component
GO_0044877	Molecular function	protein-containing complex binding
GO_0036041	Molecular function	long-chain fatty acid binding
GO_1990782	Molecular function	protein tyrosine kinase binding
GO_0005515	Molecular function	protein binding
GO_0044389	Molecular function	ubiquitin-like protein ligase binding

Gene name	PRR7
Protein name	Proline rich 7, synaptic Proline-rich protein 7 (Synaptic proline-rich membrane protein)
Synonyms
Description	FUNCTION: Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN . Might play a redundant role in the regulation of T cell receptor signaling . Might promote apoptosis in T cells . .
Accessions	D6RFJ4 ENST00000502922.5 [Q8TB68-1] ENST00000510492.1 [Q8TB68-1] Q8TB68 ENST00000507881.5 ENST00000323249.8 [Q8TB68-1]

PRR7 report