GRM3 | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	17 studies	45% ± 20%	Explore
oligodendrocyte	17 studies	61% ± 19%	Explore
glutamatergic neuron	12 studies	44% ± 19%	Explore
endothelial cell	6 studies	38% ± 15%	Explore
GABAergic neuron	6 studies	44% ± 20%	Explore
neuron	5 studies	33% ± 12%	Explore
interneuron	4 studies	52% ± 9%	Explore
pericyte	3 studies	65% ± 19%	Explore
oligodendrocyte precursor cell	3 studies	21% ± 1%	Explore

Name	Number of supported studies	Average coverage
brain	16 studies	43% ± 14%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	3902.60	2635 / 2642	97%	16.12	686 / 705
adrenal gland	12%	53.66	30 / 258	3%	0.12	8 / 230
bladder	0%	0	0 / 21	5%	0.38	26 / 504
kidney	0%	0	0 / 89	2%	0.16	22 / 901
liver	0%	0	0 / 226	2%	0.11	9 / 406
esophagus	0%	0	0 / 1445	2%	0.03	3 / 183
prostate	0%	1.47	1 / 245	1%	0.04	6 / 502
uterus	0%	0	0 / 170	2%	0.46	7 / 459
thymus	0%	0	0 / 653	1%	0.03	8 / 605
eye	0%	0	0 / 0	1%	0.03	1 / 80
pancreas	0%	0	0 / 328	1%	0.11	2 / 178
lung	0%	0	0 / 578	1%	0.03	10 / 1155
skin	0%	0	0 / 1809	1%	0.03	3 / 472
intestine	0%	0	0 / 966	0%	0.00	2 / 527
stomach	0%	0	0 / 359	0%	0.01	1 / 286
ovary	0%	0	0 / 180	0%	0.01	1 / 430
breast	0%	0	0 / 459	0%	0.00	2 / 1118
abdomen	0%	0	0 / 0	0%	0	0 / 0
adipose	0%	0	0 / 1204	0%	0	0 / 0
blood vessel	0%	0	0 / 1335	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
heart	0%	0	0 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007194	Biological process	negative regulation of adenylate cyclase activity
GO_0007196	Biological process	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
GO_0007216	Biological process	G protein-coupled glutamate receptor signaling pathway
GO_0051966	Biological process	regulation of synaptic transmission, glutamatergic
GO_0007268	Biological process	chemical synaptic transmission
GO_0099170	Biological process	postsynaptic modulation of chemical synaptic transmission
GO_0010467	Biological process	gene expression
GO_0098978	Cellular component	glutamatergic synapse
GO_0005886	Cellular component	plasma membrane
GO_0043197	Cellular component	dendritic spine
GO_0042734	Cellular component	presynaptic membrane
GO_0014069	Cellular component	postsynaptic density
GO_0097449	Cellular component	astrocyte projection
GO_0045211	Cellular component	postsynaptic membrane
GO_0030424	Cellular component	axon
GO_0001641	Molecular function	group II metabotropic glutamate receptor activity
GO_0008066	Molecular function	glutamate receptor activity
GO_0004930	Molecular function	G protein-coupled receptor activity
GO_0005246	Molecular function	calcium channel regulator activity
GO_0097110	Molecular function	scaffold protein binding

Gene name	GRM3
Protein name	Metabotropic glutamate receptor 3 (mGluR3) Metabotropic glutamate receptor 3 Glutamate metabotropic receptor 3
Synonyms	GPRC1C hCG_17203 tcag7.244 MGLUR3
Description	FUNCTION: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. . FUNCTION: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. .
Accessions	A4D1D0 ENST00000439827.1 [Q14832-2] ENST00000361669.7 [Q14832-1] ENST00000441140.1 C9J2I2 ENST00000454217.1 C9JUH9 ENST00000421579.1 Q14832 C9JIT1

GRM3 report