Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 9 studies | 39% ± 15% | |
GABAergic neuron | 7 studies | 42% ± 20% | |
amacrine cell | 6 studies | 42% ± 13% | |
neuron | 4 studies | 38% ± 12% | |
retinal ganglion cell | 4 studies | 79% ± 19% | |
retina horizontal cell | 4 studies | 27% ± 11% | |
oligodendrocyte precursor cell | 4 studies | 24% ± 6% | |
interneuron | 4 studies | 52% ± 22% | |
retinal bipolar neuron | 3 studies | 24% ± 5% | |
GABAergic interneuron | 3 studies | 35% ± 10% | |
GABAergic amacrine cell | 3 studies | 34% ± 14% | |
OFF-bipolar cell | 3 studies | 37% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 99% | 15323.25 | 2616 / 2642 | 100% | 132.62 | 703 / 705 |
adrenal gland | 64% | 1150.40 | 164 / 258 | 79% | 93.30 | 182 / 230 |
uterus | 86% | 1716.34 | 147 / 170 | 39% | 12.12 | 177 / 459 |
thymus | 14% | 170.90 | 90 / 653 | 79% | 15.92 | 477 / 605 |
blood vessel | 87% | 2087.75 | 1160 / 1335 | 0% | 0 | 0 / 0 |
skin | 24% | 456.29 | 428 / 1809 | 53% | 18.27 | 250 / 472 |
ovary | 27% | 407.67 | 49 / 180 | 41% | 6.18 | 176 / 430 |
esophagus | 32% | 476.92 | 464 / 1445 | 31% | 4.68 | 57 / 183 |
eye | 0% | 0 | 0 / 0 | 61% | 10.56 | 49 / 80 |
prostate | 47% | 656.29 | 116 / 245 | 13% | 1.13 | 64 / 502 |
pancreas | 0% | 4.42 | 1 / 328 | 55% | 8.95 | 98 / 178 |
intestine | 40% | 543.64 | 382 / 966 | 8% | 1.28 | 44 / 527 |
bladder | 19% | 277.81 | 4 / 21 | 28% | 5.62 | 141 / 504 |
lung | 3% | 40.26 | 19 / 578 | 39% | 7.31 | 448 / 1155 |
stomach | 18% | 248.68 | 66 / 359 | 14% | 2.11 | 41 / 286 |
tonsil | 0% | 0 | 0 / 0 | 29% | 4.55 | 13 / 45 |
breast | 5% | 58.14 | 24 / 459 | 16% | 2.47 | 176 / 1118 |
kidney | 6% | 61.57 | 5 / 89 | 15% | 2.06 | 136 / 901 |
liver | 0% | 0 | 0 / 226 | 7% | 0.87 | 28 / 406 |
peripheral blood | 6% | 85.87 | 57 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.21 | 1 / 29 |
adipose | 1% | 11.34 | 11 / 1204 | 0% | 0 | 0 / 0 |
spleen | 1% | 14.90 | 2 / 241 | 0% | 0 | 0 / 0 |
heart | 0% | 1.24 | 1 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0014052 | Biological process | regulation of gamma-aminobutyric acid secretion |
GO_0006874 | Biological process | intracellular calcium ion homeostasis |
GO_0016082 | Biological process | synaptic vesicle priming |
GO_0055085 | Biological process | transmembrane transport |
GO_0005911 | Cellular component | cell-cell junction |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0098982 | Cellular component | GABA-ergic synapse |
GO_0030672 | Cellular component | synaptic vesicle membrane |
GO_0048786 | Cellular component | presynaptic active zone |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0008021 | Cellular component | synaptic vesicle |
GO_0043025 | Cellular component | neuronal cell body |
GO_0005886 | Cellular component | plasma membrane |
GO_0031594 | Cellular component | neuromuscular junction |
GO_0043005 | Cellular component | neuron projection |
GO_0030425 | Cellular component | dendrite |
GO_0019901 | Molecular function | protein kinase binding |
GO_0022857 | Molecular function | transmembrane transporter activity |
Gene name | SV2A |
Protein name | Alternative protein SV2A Synaptic vesicle glycoprotein 2A |
Synonyms | PSEC0174 KIAA0736 |
Description | FUNCTION: Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity). .; FUNCTION: (Microbial infection) Receptor for the C.botulinum neurotoxin type A2 (BoNT/A, botA); glycosylation is not essential but enhances the interaction . Probably also serves as a receptor for the closely related C.botulinum neurotoxin type A1. . |
Accessions | L8E840 ENST00000369145.1 [Q7L0J3-2] Q7L0J3 ENST00000369146.8 [Q7L0J3-1] |