SV2A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0014052Biological processregulation of gamma-aminobutyric acid secretion
GO_0006874Biological processintracellular calcium ion homeostasis
GO_0016082Biological processsynaptic vesicle priming
GO_0055085Biological processtransmembrane transport
GO_0005911Cellular componentcell-cell junction
GO_0098978Cellular componentglutamatergic synapse
GO_0098982Cellular componentGABA-ergic synapse
GO_0030672Cellular componentsynaptic vesicle membrane
GO_0048786Cellular componentpresynaptic active zone
GO_0005783Cellular componentendoplasmic reticulum
GO_0008021Cellular componentsynaptic vesicle
GO_0043025Cellular componentneuronal cell body
GO_0005886Cellular componentplasma membrane
GO_0031594Cellular componentneuromuscular junction
GO_0043005Cellular componentneuron projection
GO_0030425Cellular componentdendrite
GO_0019901Molecular functionprotein kinase binding
GO_0022857Molecular functiontransmembrane transporter activity

IV. Literature review

[source]
Gene nameSV2A
Protein nameAlternative protein SV2A
Synaptic vesicle glycoprotein 2A
SynonymsPSEC0174
KIAA0736
DescriptionFUNCTION: Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity). .; FUNCTION: (Microbial infection) Receptor for the C.botulinum neurotoxin type A2 (BoNT/A, botA); glycosylation is not essential but enhances the interaction . Probably also serves as a receptor for the closely related C.botulinum neurotoxin type A1. .

AccessionsL8E840
ENST00000369145.1 [Q7L0J3-2]
Q7L0J3
ENST00000369146.8 [Q7L0J3-1]