CADPS report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015031Biological processprotein transport
GO_0006887Biological processexocytosis
GO_0016079Biological processsynaptic vesicle exocytosis
GO_0045921Biological processpositive regulation of exocytosis
GO_1990504Biological processdense core granule exocytosis
GO_0098978Cellular componentglutamatergic synapse
GO_0098793Cellular componentpresynapse
GO_0005829Cellular componentcytosol
GO_0099012Cellular componentneuronal dense core vesicle membrane
GO_0019901Molecular functionprotein kinase binding
GO_0005515Molecular functionprotein binding
GO_0008289Molecular functionlipid binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameCADPS
Protein nameCalcium dependent secretion activator
CADPS protein
Calcium dependent secretion activator (Calcium-dependent secretion activator 1)
Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1)
SynonymsCAPS
CAPS1
KIAA1121
DescriptionFUNCTION: Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates catecholamine loading of DCVs. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles by acting as a PtdIns(4,5)P2-binding protein that acts at prefusion step following ATP-dependent priming and participates in DCVs-membrane fusion. However, it may also participate in small clear synaptic vesicles (SVs) exocytosis and it is unclear whether its function is related to Ca(2+) triggering (By similarity). .

AccessionsENST00000612439.4
ENST00000283269.13 [Q9ULU8-3]
ENST00000466621.2
H7C538
ENST00000383710.9 [Q9ULU8-1]
H0YFP0
ENST00000613879.4
A0A0C4DGY2
F1T0E5
ENST00000468271.5
ENST00000357948.7 [Q9ULU8-2]
ENST00000473635.5
H7C4T6
ENST00000490353.2 [Q9ULU8-5]
ENST00000542833.1
H7C4P2
ENST00000491424.5
Q9ULU8
A2RRN7
H7C4K9