STAU1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0046726Biological processpositive regulation by virus of viral protein levels in host cell
GO_0099010Biological processmodification of postsynaptic structure
GO_0098964Biological processanterograde dendritic transport of messenger ribonucleoprotein complex
GO_0045070Biological processpositive regulation of viral genome replication
GO_0034599Biological processcellular response to oxidative stress
GO_0007281Biological processgerm cell development
GO_1900273Biological processpositive regulation of long-term synaptic potentiation
GO_0008298Biological processintracellular mRNA localization
GO_0000512Biological processlncRNA-mediated post-transcriptional gene silencing
GO_0035418Biological processprotein localization to synapse
GO_0098978Cellular componentglutamatergic synapse
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0036464Cellular componentcytoplasmic ribonucleoprotein granule
GO_0070062Cellular componentextracellular exosome
GO_0043025Cellular componentneuronal cell body
GO_0043005Cellular componentneuron projection
GO_0030425Cellular componentdendrite
GO_0005783Cellular componentendoplasmic reticulum
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0044297Cellular componentcell body
GO_1990124Cellular componentmessenger ribonucleoprotein complex
GO_0005791Cellular componentrough endoplasmic reticulum
GO_0032839Cellular componentdendrite cytoplasm
GO_0005875Cellular componentmicrotubule associated complex
GO_0010494Cellular componentcytoplasmic stress granule
GO_0003729Molecular functionmRNA binding
GO_0008157Molecular functionprotein phosphatase 1 binding
GO_0003723Molecular functionRNA binding
GO_0005515Molecular functionprotein binding
GO_0003725Molecular functiondouble-stranded RNA binding

IV. Literature review

[source]
Gene nameSTAU1
Protein nameDouble-stranded RNA-binding protein Staufen homolog 1
STAU1 protein
Staufen double-stranded RNA binding protein 1
SynonymsSTAU
DescriptionFUNCTION: Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.; FUNCTION: (Microbial infection) Plays a role in virus particles production of many viruses including of HIV-1, HERV-K, ebola virus and influenza virus. Acts by interacting with various viral proteins involved in particle budding process. .

AccessionsENST00000347458.9 [O95793-2]
Q6PJX3
ENST00000371828.7 [O95793-3]
ENST00000371792.5
ENST00000371802.5 [O95793-3]
Q5JW30
ENST00000456866.2
ENST00000360426.8 [O95793-2]
ENST00000437404.2
Q5JW28
O95793
ENST00000340954.11 [O95793-2]
ENST00000371856.7 [O95793-1]
F6UDC6