CHRM1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CHRM1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHRM1 at tissue level.

III. Associated gene sets

GO_0007197Biological processadenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway
GO_0007213Biological processG protein-coupled acetylcholine receptor signaling pathway
GO_0007207Biological processphospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway
GO_0007165Biological processsignal transduction
GO_0046541Biological processsaliva secretion
GO_0043270Biological processpositive regulation of monoatomic ion transport
GO_0098664Biological processG protein-coupled serotonin receptor signaling pathway
GO_0007274Biological processneuromuscular synaptic transmission
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007268Biological processchemical synaptic transmission
GO_0060251Biological processregulation of glial cell proliferation
GO_0040012Biological processregulation of locomotion
GO_0007187Biological processG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO_0060078Biological processregulation of postsynaptic membrane potential
GO_0050890Biological processcognition
GO_0099170Biological processpostsynaptic modulation of chemical synaptic transmission
GO_0090316Biological processpositive regulation of intracellular protein transport
GO_0007399Biological processnervous system development
GO_0007205Biological processprotein kinase C-activating G protein-coupled receptor signaling pathway
GO_0098978Cellular componentglutamatergic synapse
GO_0098839Cellular componentpostsynaptic density membrane
GO_0098685Cellular componentSchaffer collateral - CA1 synapse
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0043679Cellular componentaxon terminus
GO_0042734Cellular componentpresynaptic membrane
GO_0030425Cellular componentdendrite
GO_0098981Cellular componentcholinergic synapse
GO_0045202Cellular componentsynapse
GO_0004435Molecular functionphosphatidylinositol phospholipase C activity
GO_0004993Molecular functionG protein-coupled serotonin receptor activity
GO_0016907Molecular functionG protein-coupled acetylcholine receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCHRM1
Protein nameMuscarinic acetylcholine receptor
Muscarinic acetylcholine receptor M1
SynonymshCG_2020133
DescriptionFUNCTION: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

FUNCTION: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. .

FUNCTION: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. .

AccessionsENST00000306960.4 [P11229-1]
Q53XZ3
ENST00000536524.1
P11229
ENST00000543973.1 [P11229-2]
F5GZF8