CACNG4 | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte precursor cell	13 studies	46% ± 16%	Explore
GABAergic neuron	5 studies	31% ± 9%	Explore
interneuron	4 studies	23% ± 3%	Explore
neuron	3 studies	27% ± 7%	Explore

Name	Number of supported studies	Average coverage
brain	5 studies	21% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	3154.77	2634 / 2642	97%	154.35	682 / 705
prostate	83%	1239.09	204 / 245	68%	25.78	339 / 502
breast	52%	740.65	238 / 459	81%	85.36	900 / 1118
lung	89%	779.95	514 / 578	27%	8.81	313 / 1155
ovary	1%	2.78	1 / 180	75%	34.04	322 / 430
adrenal gland	5%	19.93	14 / 258	53%	26.92	121 / 230
stomach	32%	99.96	116 / 359	14%	3.51	39 / 286
uterus	8%	46.21	14 / 170	37%	11.94	168 / 459
pancreas	1%	2.10	3 / 328	37%	11.67	66 / 178
esophagus	16%	86.27	234 / 1445	18%	4.12	33 / 183
bladder	5%	9.71	1 / 21	23%	7.79	118 / 504
intestine	5%	26.52	53 / 966	13%	3.23	71 / 527
thymus	1%	3.36	7 / 653	16%	3.02	97 / 605
tonsil	0%	0	0 / 0	13%	2.40	6 / 45
liver	0%	0	0 / 226	11%	4.46	44 / 406
skin	4%	11.13	71 / 1809	4%	1.20	17 / 472
adipose	5%	14.04	60 / 1204	0%	0	0 / 0
kidney	0%	0	0 / 89	1%	0.31	10 / 901
heart	1%	2.88	6 / 861	0%	0	0 / 0
muscle	0%	0.61	2 / 803	0%	0	0 / 0
blood vessel	0%	0.19	1 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0098970	Biological process	postsynaptic neurotransmitter receptor diffusion trapping
GO_0042220	Biological process	response to cocaine
GO_0099590	Biological process	neurotransmitter receptor internalization
GO_2000311	Biological process	regulation of AMPA receptor activity
GO_0098943	Biological process	neurotransmitter receptor transport, postsynaptic endosome to lysosome
GO_0051968	Biological process	positive regulation of synaptic transmission, glutamatergic
GO_0019226	Biological process	transmission of nerve impulse
GO_0070588	Biological process	calcium ion transmembrane transport
GO_0098978	Cellular component	glutamatergic synapse
GO_0098839	Cellular component	postsynaptic density membrane
GO_0005886	Cellular component	plasma membrane
GO_1990454	Cellular component	L-type voltage-gated calcium channel complex
GO_0036477	Cellular component	somatodendritic compartment
GO_0030666	Cellular component	endocytic vesicle membrane
GO_0032281	Cellular component	AMPA glutamate receptor complex
GO_0009986	Cellular component	cell surface
GO_0044297	Cellular component	cell body
GO_0005246	Molecular function	calcium channel regulator activity
GO_0005245	Molecular function	voltage-gated calcium channel activity
GO_0016247	Molecular function	channel regulator activity
GO_0035255	Molecular function	ionotropic glutamate receptor binding

Gene name	CACNG4
Protein name	Voltage-dependent calcium channel gamma-4 subunit (Neuronal voltage-gated calcium channel gamma-4 subunit) (Transmembrane AMPAR regulatory protein gamma-4) (TARP gamma-4)
Synonyms
Description	FUNCTION: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit . Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization . .
Accessions	ENST00000262138.4 Q9UBN1

CACNG4 report