P2RY1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of P2RY1 at tissue level.

III. Associated gene sets

GO_0072659Biological processprotein localization to plasma membrane
GO_0060406Biological processpositive regulation of penile erection
GO_0007200Biological processphospholipase C-activating G protein-coupled receptor signaling pathway
GO_0006811Biological processmonoatomic ion transport
GO_0001973Biological processG protein-coupled adenosine receptor signaling pathway
GO_0043270Biological processpositive regulation of monoatomic ion transport
GO_0001934Biological processpositive regulation of protein phosphorylation
GO_0097746Biological processblood vessel diameter maintenance
GO_0051649Biological processestablishment of localization in cell
GO_0071318Biological processcellular response to ATP
GO_0030168Biological processplatelet activation
GO_0023019Biological processsignal transduction involved in regulation of gene expression
GO_0071415Biological processcellular response to purine-containing compound
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007204Biological processpositive regulation of cytosolic calcium ion concentration
GO_0007193Biological processadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO_0032962Biological processpositive regulation of inositol trisphosphate biosynthetic process
GO_0035589Biological processG protein-coupled purinergic nucleotide receptor signaling pathway
GO_0090075Biological processrelaxation of muscle
GO_0042755Biological processeating behavior
GO_0099509Biological processregulation of presynaptic cytosolic calcium ion concentration
GO_0008347Biological processglial cell migration
GO_0008360Biological processregulation of cell shape
GO_0009612Biological processresponse to mechanical stimulus
GO_0046887Biological processpositive regulation of hormone secretion
GO_0070374Biological processpositive regulation of ERK1 and ERK2 cascade
GO_0010700Biological processnegative regulation of norepinephrine secretion
GO_0070848Biological processresponse to growth factor
GO_2000300Biological processregulation of synaptic vesicle exocytosis
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0007166Biological processcell surface receptor signaling pathway
GO_0016323Cellular componentbasolateral plasma membrane
GO_0016324Cellular componentapical plasma membrane
GO_0098978Cellular componentglutamatergic synapse
GO_0005886Cellular componentplasma membrane
GO_0048787Cellular componentpresynaptic active zone membrane
GO_0030425Cellular componentdendrite
GO_0009986Cellular componentcell surface
GO_0005929Cellular componentcilium
GO_0014069Cellular componentpostsynaptic density
GO_0045211Cellular componentpostsynaptic membrane
GO_0044297Cellular componentcell body
GO_0045031Molecular functionG protein-coupled ATP receptor activity
GO_0043531Molecular functionADP binding
GO_0038023Molecular functionsignaling receptor activity
GO_0031686Molecular functionA1 adenosine receptor binding
GO_0097110Molecular functionscaffold protein binding
GO_0005524Molecular functionATP binding
GO_0045028Molecular functionG protein-coupled purinergic nucleotide receptor activity
GO_0046982Molecular functionprotein heterodimerization activity
GO_0001621Molecular functionG protein-coupled ADP receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameP2RY1
Protein nameP2Y purinoceptor 1 (P2Y1) (ADP receptor) (Purinergic receptor)
Synonyms
DescriptionFUNCTION: Receptor for extracellular adenine nucleotides such as ADP . In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation . .

AccessionsP47900
ENST00000305097.6