Insufficient scRNA-seq data for expression of P2RY1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 96% | 1149.67 | 236 / 245 | 91% | 18.58 | 457 / 502 |
brain | 80% | 1032.14 | 2110 / 2642 | 88% | 18.48 | 622 / 705 |
uterus | 98% | 1736.44 | 167 / 170 | 63% | 15.05 | 290 / 459 |
lung | 100% | 2458.61 | 577 / 578 | 59% | 13.78 | 683 / 1155 |
intestine | 99% | 2373.46 | 960 / 966 | 49% | 3.49 | 256 / 527 |
pancreas | 78% | 432.73 | 257 / 328 | 61% | 4.84 | 109 / 178 |
esophagus | 71% | 1696.16 | 1019 / 1445 | 63% | 17.44 | 116 / 183 |
bladder | 90% | 529.86 | 19 / 21 | 39% | 4.33 | 199 / 504 |
ovary | 99% | 1170.58 | 179 / 180 | 16% | 0.82 | 68 / 430 |
skin | 72% | 1350.61 | 1301 / 1809 | 42% | 3.63 | 198 / 472 |
tonsil | 0% | 0 | 0 / 0 | 93% | 28.87 | 42 / 45 |
spleen | 86% | 691.51 | 207 / 241 | 0% | 0 | 0 / 0 |
adrenal gland | 64% | 265.19 | 165 / 258 | 13% | 0.64 | 31 / 230 |
adipose | 74% | 402.68 | 889 / 1204 | 0% | 0 | 0 / 0 |
heart | 67% | 318.81 | 575 / 861 | 0% | 0 | 0 / 0 |
kidney | 12% | 41.37 | 11 / 89 | 52% | 5.16 | 470 / 901 |
thymus | 50% | 186.65 | 328 / 653 | 11% | 0.44 | 66 / 605 |
stomach | 30% | 202.29 | 106 / 359 | 28% | 1.74 | 81 / 286 |
breast | 40% | 181.28 | 183 / 459 | 12% | 0.62 | 136 / 1118 |
muscle | 40% | 250.47 | 325 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 29% | 121.41 | 383 / 1335 | 0% | 0 | 0 / 0 |
liver | 12% | 46.02 | 28 / 226 | 8% | 0.48 | 33 / 406 |
peripheral blood | 18% | 98.38 | 168 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 3% | 0.15 | 2 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0072659 | Biological process | protein localization to plasma membrane |
GO_0060406 | Biological process | positive regulation of penile erection |
GO_0007200 | Biological process | phospholipase C-activating G protein-coupled receptor signaling pathway |
GO_0006811 | Biological process | monoatomic ion transport |
GO_0001973 | Biological process | G protein-coupled adenosine receptor signaling pathway |
GO_0043270 | Biological process | positive regulation of monoatomic ion transport |
GO_0001934 | Biological process | positive regulation of protein phosphorylation |
GO_0097746 | Biological process | blood vessel diameter maintenance |
GO_0051649 | Biological process | establishment of localization in cell |
GO_0071318 | Biological process | cellular response to ATP |
GO_0030168 | Biological process | platelet activation |
GO_0023019 | Biological process | signal transduction involved in regulation of gene expression |
GO_0071415 | Biological process | cellular response to purine-containing compound |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
GO_0007193 | Biological process | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway |
GO_0032962 | Biological process | positive regulation of inositol trisphosphate biosynthetic process |
GO_0035589 | Biological process | G protein-coupled purinergic nucleotide receptor signaling pathway |
GO_0090075 | Biological process | relaxation of muscle |
GO_0042755 | Biological process | eating behavior |
GO_0099509 | Biological process | regulation of presynaptic cytosolic calcium ion concentration |
GO_0008347 | Biological process | glial cell migration |
GO_0008360 | Biological process | regulation of cell shape |
GO_0009612 | Biological process | response to mechanical stimulus |
GO_0046887 | Biological process | positive regulation of hormone secretion |
GO_0070374 | Biological process | positive regulation of ERK1 and ERK2 cascade |
GO_0010700 | Biological process | negative regulation of norepinephrine secretion |
GO_0070848 | Biological process | response to growth factor |
GO_2000300 | Biological process | regulation of synaptic vesicle exocytosis |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0007166 | Biological process | cell surface receptor signaling pathway |
GO_0016323 | Cellular component | basolateral plasma membrane |
GO_0016324 | Cellular component | apical plasma membrane |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0048787 | Cellular component | presynaptic active zone membrane |
GO_0030425 | Cellular component | dendrite |
GO_0009986 | Cellular component | cell surface |
GO_0005929 | Cellular component | cilium |
GO_0014069 | Cellular component | postsynaptic density |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_0044297 | Cellular component | cell body |
GO_0045031 | Molecular function | G protein-coupled ATP receptor activity |
GO_0043531 | Molecular function | ADP binding |
GO_0038023 | Molecular function | signaling receptor activity |
GO_0031686 | Molecular function | A1 adenosine receptor binding |
GO_0097110 | Molecular function | scaffold protein binding |
GO_0005524 | Molecular function | ATP binding |
GO_0045028 | Molecular function | G protein-coupled purinergic nucleotide receptor activity |
GO_0046982 | Molecular function | protein heterodimerization activity |
GO_0001621 | Molecular function | G protein-coupled ADP receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | P2RY1 |
Protein name | P2Y purinoceptor 1 (P2Y1) (ADP receptor) (Purinergic receptor) |
Synonyms | |
Description | FUNCTION: Receptor for extracellular adenine nucleotides such as ADP . In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation . . |
Accessions | P47900 ENST00000305097.6 |