Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 7 studies | 27% ± 11% | |
| basal cell | 6 studies | 28% ± 13% | |
| retinal ganglion cell | 4 studies | 50% ± 26% | |
| endothelial cell | 4 studies | 22% ± 5% | |
| neuron | 4 studies | 29% ± 14% | |
| keratinocyte | 4 studies | 21% ± 5% | |
| ciliated cell | 3 studies | 35% ± 6% |
Insufficient scRNA-seq data for expression of HRAS at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 3010.88 | 1445 / 1445 | 100% | 55.95 | 183 / 183 |
| uterus | 100% | 1495.92 | 170 / 170 | 100% | 112.94 | 459 / 459 |
| brain | 100% | 3850.37 | 2641 / 2642 | 100% | 80.64 | 705 / 705 |
| thymus | 100% | 1478.51 | 651 / 653 | 100% | 68.29 | 604 / 605 |
| skin | 100% | 4279.64 | 1809 / 1809 | 99% | 70.67 | 469 / 472 |
| prostate | 100% | 2782.19 | 245 / 245 | 99% | 77.15 | 498 / 502 |
| kidney | 100% | 1926.26 | 89 / 89 | 99% | 50.02 | 891 / 901 |
| intestine | 100% | 1661.75 | 966 / 966 | 99% | 51.88 | 521 / 527 |
| ovary | 99% | 1199.38 | 179 / 180 | 99% | 36.46 | 427 / 430 |
| bladder | 100% | 2310.76 | 21 / 21 | 98% | 101.07 | 496 / 504 |
| adrenal gland | 99% | 1285.37 | 256 / 258 | 99% | 70.56 | 228 / 230 |
| lung | 100% | 1733.25 | 576 / 578 | 98% | 65.59 | 1135 / 1155 |
| stomach | 99% | 1196.16 | 356 / 359 | 98% | 42.05 | 281 / 286 |
| breast | 100% | 1805.88 | 459 / 459 | 97% | 59.16 | 1087 / 1118 |
| liver | 87% | 713.69 | 197 / 226 | 98% | 39.33 | 398 / 406 |
| pancreas | 86% | 697.12 | 281 / 328 | 99% | 61.67 | 177 / 178 |
| eye | 0% | 0 | 0 / 0 | 100% | 73.33 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 71.84 | 29 / 29 |
| spleen | 100% | 1504.74 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 124.17 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 162.20 | 1 / 1 |
| adipose | 100% | 1586.51 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1856.40 | 1330 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 99% | 1835.67 | 795 / 803 | 0% | 0 | 0 / 0 |
| heart | 98% | 1590.11 | 847 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 39% | 383.82 | 358 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0032956 | Biological process | regulation of actin cytoskeleton organization |
| GO_0007265 | Biological process | Ras protein signal transduction |
| GO_0008285 | Biological process | negative regulation of cell population proliferation |
| GO_0048146 | Biological process | positive regulation of fibroblast proliferation |
| GO_0034260 | Biological process | negative regulation of GTPase activity |
| GO_0006897 | Biological process | endocytosis |
| GO_0048169 | Biological process | regulation of long-term neuronal synaptic plasticity |
| GO_0042552 | Biological process | myelination |
| GO_0043547 | Biological process | positive regulation of GTPase activity |
| GO_0000165 | Biological process | MAPK cascade |
| GO_0010629 | Biological process | negative regulation of gene expression |
| GO_0090402 | Biological process | oncogene-induced cell senescence |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0009887 | Biological process | animal organ morphogenesis |
| GO_0042832 | Biological process | defense response to protozoan |
| GO_0007165 | Biological process | signal transduction |
| GO_0046330 | Biological process | positive regulation of JNK cascade |
| GO_1900029 | Biological process | positive regulation of ruffle assembly |
| GO_2000630 | Biological process | positive regulation of miRNA metabolic process |
| GO_0006935 | Biological process | chemotaxis |
| GO_0001934 | Biological process | positive regulation of protein phosphorylation |
| GO_0043410 | Biological process | positive regulation of MAPK cascade |
| GO_0050852 | Biological process | T cell receptor signaling pathway |
| GO_0071480 | Biological process | cellular response to gamma radiation |
| GO_0043406 | Biological process | positive regulation of MAP kinase activity |
| GO_0051402 | Biological process | neuron apoptotic process |
| GO_0097193 | Biological process | intrinsic apoptotic signaling pathway |
| GO_0050679 | Biological process | positive regulation of epithelial cell proliferation |
| GO_0008286 | Biological process | insulin receptor signaling pathway |
| GO_0014044 | Biological process | Schwann cell development |
| GO_0042088 | Biological process | T-helper 1 type immune response |
| GO_0030335 | Biological process | positive regulation of cell migration |
| GO_0048144 | Biological process | fibroblast proliferation |
| GO_0090314 | Biological process | positive regulation of protein targeting to membrane |
| GO_0060612 | Biological process | adipose tissue development |
| GO_0098696 | Biological process | regulation of neurotransmitter receptor localization to postsynaptic specialization membrane |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0090398 | Biological process | cellular senescence |
| GO_0032729 | Biological process | positive regulation of type II interferon production |
| GO_0043524 | Biological process | negative regulation of neuron apoptotic process |
| GO_0070374 | Biological process | positive regulation of ERK1 and ERK2 cascade |
| GO_0042127 | Biological process | regulation of cell population proliferation |
| GO_0051726 | Biological process | regulation of cell cycle |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0090303 | Biological process | positive regulation of wound healing |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_1905360 | Cellular component | GTPase complex |
| GO_0019003 | Molecular function | GDP binding |
| GO_0003924 | Molecular function | GTPase activity |
| GO_0043495 | Molecular function | protein-membrane adaptor activity |
| GO_0003925 | Molecular function | G protein activity |
| GO_0005525 | Molecular function | GTP binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | HRAS |
| Protein name | p21 protein GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed] GTPase HRas GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Transforming protein p21) (c-H-ras) (p21ras) HRas proto-oncogene, GTPase |
| Synonyms | HRAS1 |
| Description | FUNCTION: Involved in the activation of Ras protein signal transduction . Ras proteins bind GDP/GTP and possess intrinsic GTPase activity . . |
| Accessions | ENST00000451590.5 [P01112-1] ENST00000397594.6 ENST00000311189.8 [P01112-1] ENST00000462734.2 ENST00000616241.4 [P01112-2] A0A0J9YXG8 ENST00000397594.7 [P01112-2] X5D945 A0A804HKM6 ENST00000468682.2 ENST00000615062.2 [P01112-1] P01112 A0A8C8MQR2 ENST00000417302.7 [P01112-2] A0A804HJ06 ENST00000397596.6 [P01112-1] ENST00000631404.1 [P01112-1] ENST00000633700.1 ENST00000493230.5 [P01112-2] ENST00000631967.1 [P01112-2] ENST00000634098.1 [P01112-2] P78460 ENST00000610977.3 [P01112-1] |
