I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 4 studies | 35% ± 10% | |
| glutamatergic neuron | 4 studies | 41% ± 18% | |
| neuron | 3 studies | 18% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 4 studies | 35% ± 10% | |
| glutamatergic neuron | 4 studies | 41% ± 18% | |
| neuron | 3 studies | 18% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 33% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 97% | 7924.28 | 2553 / 2642 | 100% | 36.97 | 705 / 705 |
| lung | 96% | 1601.84 | 555 / 578 | 83% | 5.25 | 961 / 1155 |
| breast | 93% | 1219.31 | 426 / 459 | 81% | 4.18 | 908 / 1118 |
| uterus | 99% | 4765.19 | 168 / 170 | 71% | 6.64 | 328 / 459 |
| prostate | 94% | 1680.38 | 230 / 245 | 74% | 3.90 | 373 / 502 |
| stomach | 87% | 1859.02 | 314 / 359 | 80% | 6.96 | 228 / 286 |
| ovary | 100% | 3513.15 | 180 / 180 | 67% | 3.09 | 288 / 430 |
| pancreas | 76% | 1466.95 | 249 / 328 | 89% | 6.22 | 159 / 178 |
| thymus | 91% | 1191.88 | 597 / 653 | 72% | 3.32 | 434 / 605 |
| bladder | 95% | 1776.10 | 20 / 21 | 67% | 3.57 | 336 / 504 |
| esophagus | 68% | 1760.43 | 976 / 1445 | 91% | 8.08 | 166 / 183 |
| intestine | 85% | 3369.28 | 822 / 966 | 70% | 4.53 | 367 / 527 |
| kidney | 70% | 839.84 | 62 / 89 | 75% | 5.08 | 676 / 901 |
| skin | 46% | 1173.85 | 825 / 1809 | 94% | 11.30 | 445 / 472 |
| adrenal gland | 53% | 625.15 | 136 / 258 | 66% | 4.26 | 152 / 230 |
| adipose | 94% | 1524.73 | 1130 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 92% | 1538.27 | 1232 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 90% | 9.28 | 72 / 80 |
| spleen | 86% | 1056.19 | 208 / 241 | 0% | 0 | 0 / 0 |
| heart | 77% | 1058.67 | 664 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 76% | 11.43 | 22 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 62% | 3.26 | 28 / 45 |
| liver | 1% | 11.71 | 3 / 226 | 23% | 1.27 | 95 / 406 |
| muscle | 23% | 218.08 | 184 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 19% | 906.99 | 174 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0098529 | Biological process | neuromuscular junction development, skeletal muscle fiber |
| GO_1990227 | Biological process | paranodal junction maintenance |
| GO_0007165 | Biological process | signal transduction |
| GO_0097106 | Biological process | postsynaptic density organization |
| GO_0050885 | Biological process | neuromuscular process controlling balance |
| GO_0007155 | Biological process | cell adhesion |
| GO_0007010 | Biological process | cytoskeleton organization |
| GO_0050884 | Biological process | neuromuscular process controlling posture |
| GO_0022010 | Biological process | central nervous system myelination |
| GO_0022011 | Biological process | myelination in peripheral nervous system |
| GO_0007409 | Biological process | axonogenesis |
| GO_0048812 | Biological process | neuron projection morphogenesis |
| GO_0007005 | Biological process | mitochondrion organization |
| GO_0002175 | Biological process | protein localization to paranode region of axon |
| GO_0030913 | Biological process | paranodal junction assembly |
| GO_0071205 | Biological process | protein localization to juxtaparanode region of axon |
| GO_0090128 | Biological process | regulation of synapse maturation |
| GO_0019227 | Biological process | neuronal action potential propagation |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0048786 | Cellular component | presynaptic active zone |
| GO_0033010 | Cellular component | paranodal junction |
| GO_0033270 | Cellular component | paranode region of axon |
| GO_0038023 | Molecular function | signaling receptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0017124 | Molecular function | SH3 domain binding |
| Gene name | CNTNAP1 |
| Protein name | Contactin associated protein 1 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) Alternative protein CNTNAP1 |
| Synonyms | NRXN4 CASPR |
| Description | FUNCTION: Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells. . |
| Accessions | P78357 ENST00000264638.9 ENST00000591662.1 L8E7H9 K7EMM9 |
