Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 22 studies | 64% ± 21% | |
oligodendrocyte precursor cell | 15 studies | 82% ± 16% | |
glutamatergic neuron | 12 studies | 75% ± 22% | |
GABAergic neuron | 11 studies | 66% ± 21% | |
retinal ganglion cell | 7 studies | 62% ± 17% | |
retinal cone cell | 7 studies | 57% ± 29% | |
pericyte | 6 studies | 33% ± 17% | |
endothelial cell | 6 studies | 41% ± 23% | |
neuron | 6 studies | 65% ± 19% | |
interneuron | 6 studies | 69% ± 25% | |
amacrine cell | 6 studies | 58% ± 29% | |
Mueller cell | 6 studies | 40% ± 22% | |
mast cell | 5 studies | 23% ± 7% | |
granule cell | 4 studies | 61% ± 20% | |
microglial cell | 4 studies | 30% ± 15% | |
retinal bipolar neuron | 4 studies | 31% ± 14% | |
OFF-bipolar cell | 4 studies | 49% ± 14% | |
ON-bipolar cell | 4 studies | 57% ± 17% | |
adipocyte | 4 studies | 19% ± 3% | |
macrophage | 3 studies | 30% ± 15% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 74% ± 10% | |
GABAergic interneuron | 3 studies | 72% ± 0% | |
GABAergic amacrine cell | 3 studies | 53% ± 12% | |
glycinergic amacrine cell | 3 studies | 45% ± 19% | |
rod bipolar cell | 3 studies | 26% ± 9% | |
retinal rod cell | 3 studies | 45% ± 33% | |
ependymal cell | 3 studies | 51% ± 17% | |
oligodendrocyte | 3 studies | 37% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 12398.85 | 2636 / 2642 | 100% | 215.19 | 702 / 705 |
adrenal gland | 100% | 10691.40 | 257 / 258 | 89% | 80.76 | 204 / 230 |
pancreas | 98% | 3069.51 | 322 / 328 | 32% | 7.38 | 57 / 178 |
kidney | 47% | 821.58 | 42 / 89 | 66% | 17.67 | 596 / 901 |
thymus | 11% | 176.49 | 74 / 653 | 86% | 26.20 | 521 / 605 |
spleen | 76% | 2012.15 | 182 / 241 | 0% | 0 | 0 / 0 |
ovary | 9% | 156.11 | 16 / 180 | 54% | 11.23 | 234 / 430 |
skin | 28% | 2809.66 | 515 / 1809 | 30% | 9.66 | 143 / 472 |
lung | 25% | 405.24 | 147 / 578 | 31% | 12.08 | 362 / 1155 |
tonsil | 0% | 0 | 0 / 0 | 42% | 8.48 | 19 / 45 |
breast | 22% | 566.63 | 99 / 459 | 19% | 5.20 | 214 / 1118 |
esophagus | 2% | 28.04 | 26 / 1445 | 28% | 10.26 | 52 / 183 |
adipose | 28% | 783.42 | 332 / 1204 | 0% | 0 | 0 / 0 |
prostate | 3% | 52.47 | 7 / 245 | 17% | 3.03 | 86 / 502 |
uterus | 1% | 14.20 | 2 / 170 | 18% | 5.15 | 84 / 459 |
eye | 0% | 0 | 0 / 0 | 18% | 3.00 | 14 / 80 |
lymph node | 0% | 0 | 0 / 0 | 17% | 2.11 | 5 / 29 |
stomach | 1% | 7.40 | 2 / 359 | 16% | 3.63 | 45 / 286 |
liver | 0% | 0 | 0 / 226 | 14% | 3.19 | 56 / 406 |
intestine | 1% | 14.32 | 10 / 966 | 10% | 2.18 | 55 / 527 |
bladder | 0% | 0 | 0 / 21 | 10% | 3.58 | 50 / 504 |
peripheral blood | 3% | 96.16 | 26 / 929 | 0% | 0 | 0 / 0 |
blood vessel | 1% | 8.06 | 7 / 1335 | 0% | 0 | 0 / 0 |
heart | 0% | 2.42 | 2 / 861 | 0% | 0 | 0 / 0 |
muscle | 0% | 1.31 | 1 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0001525 | Biological process | angiogenesis |
GO_0030516 | Biological process | regulation of axon extension |
GO_0099175 | Biological process | regulation of postsynapse organization |
GO_0045162 | Biological process | clustering of voltage-gated sodium channels |
GO_0001764 | Biological process | neuron migration |
GO_0034113 | Biological process | heterotypic cell-cell adhesion |
GO_0007413 | Biological process | axonal fasciculation |
GO_0007409 | Biological process | axonogenesis |
GO_0007417 | Biological process | central nervous system development |
GO_0007420 | Biological process | brain development |
GO_0010975 | Biological process | regulation of neuron projection development |
GO_0008104 | Biological process | protein localization |
GO_0007416 | Biological process | synapse assembly |
GO_0045666 | Biological process | positive regulation of neuron differentiation |
GO_0031290 | Biological process | retinal ganglion cell axon guidance |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0007411 | Biological process | axon guidance |
GO_0019227 | Biological process | neuronal action potential propagation |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0098839 | Cellular component | postsynaptic density membrane |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0043194 | Cellular component | axon initial segment |
GO_0043005 | Cellular component | neuron projection |
GO_0030424 | Cellular component | axon |
GO_0086080 | Molecular function | protein binding involved in heterotypic cell-cell adhesion |
GO_0098632 | Molecular function | cell-cell adhesion mediator activity |
GO_0030506 | Molecular function | ankyrin binding |
GO_0005515 | Molecular function | protein binding |
Gene name | NRCAM |
Protein name | Neuronal cell adhesion molecule short isoform Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (hBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) Neuronal cell adhesion molecule NRCAM protein Uncharacterized protein NRCAM |
Synonyms | KIAA0343 |
Description | FUNCTION: Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier. . |
Accessions | Q14CA1 Q6QRP2 ENST00000351718.8 [Q92823-4] ENST00000419936.5 Q92823 ENST00000445634.2 C9J8B6 ENST00000418239.1 A0A1B1PFW4 C9JH43 C9JYY6 C9JUR7 C9JF43 ENST00000379024.8 [Q92823-6] ENST00000413765.6 Q4KMQ7 ENST00000442580.5 A0A1S5UZH4 ENST00000417701.5 Q75ML9 ENST00000456431.5 ENST00000379028.8 [Q92823-1] H7C132 |