Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 10 studies | 36% ± 14% | |
| neuron | 6 studies | 28% ± 10% | |
| retinal ganglion cell | 5 studies | 69% ± 20% | |
| GABAergic neuron | 5 studies | 40% ± 5% | |
| pancreatic A cell | 4 studies | 36% ± 17% | |
| type B pancreatic cell | 3 studies | 46% ± 12% | |
| amacrine cell | 3 studies | 23% ± 8% | |
| rod bipolar cell | 3 studies | 27% ± 8% | |
| interneuron | 3 studies | 40% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 89% | 7994.38 | 2339 / 2642 | 74% | 22.91 | 525 / 705 |
| adrenal gland | 16% | 266.50 | 40 / 258 | 67% | 200.93 | 153 / 230 |
| pancreas | 2% | 19.19 | 8 / 328 | 51% | 11.83 | 90 / 178 |
| adipose | 20% | 311.41 | 235 / 1204 | 0% | 0 | 0 / 0 |
| prostate | 2% | 19.84 | 6 / 245 | 16% | 5.14 | 81 / 502 |
| intestine | 8% | 52.85 | 73 / 966 | 3% | 1.19 | 17 / 527 |
| uterus | 0% | 0 | 0 / 170 | 6% | 1.13 | 29 / 459 |
| heart | 6% | 92.70 | 49 / 861 | 0% | 0 | 0 / 0 |
| lung | 1% | 15.96 | 8 / 578 | 4% | 1.51 | 42 / 1155 |
| ovary | 3% | 21.33 | 5 / 180 | 1% | 0.14 | 5 / 430 |
| stomach | 1% | 10.92 | 4 / 359 | 3% | 1.34 | 8 / 286 |
| breast | 0% | 0 | 0 / 459 | 3% | 1.80 | 39 / 1118 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.38 | 2 / 80 |
| bladder | 0% | 0 | 0 / 21 | 1% | 0.21 | 6 / 504 |
| esophagus | 0% | 1.23 | 3 / 1445 | 1% | 0.14 | 1 / 183 |
| liver | 0% | 0 | 0 / 226 | 1% | 0.08 | 3 / 406 |
| kidney | 0% | 0 | 0 / 89 | 1% | 0.35 | 6 / 901 |
| thymus | 0% | 2.11 | 2 / 653 | 0% | 0.02 | 2 / 605 |
| blood vessel | 0% | 6.49 | 6 / 1335 | 0% | 0 | 0 / 0 |
| skin | 0% | 2.71 | 4 / 1809 | 0% | 0.01 | 1 / 472 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0014059 | Biological process | regulation of dopamine secretion |
| GO_0099519 | Biological process | dense core granule cytoskeletal transport |
| GO_2000301 | Biological process | negative regulation of synaptic vesicle exocytosis |
| GO_0048791 | Biological process | calcium ion-regulated exocytosis of neurotransmitter |
| GO_0014049 | Biological process | positive regulation of glutamate secretion |
| GO_0031338 | Biological process | regulation of vesicle fusion |
| GO_1903861 | Biological process | positive regulation of dendrite extension |
| GO_0050709 | Biological process | negative regulation of protein secretion |
| GO_0048174 | Biological process | negative regulation of short-term neuronal synaptic plasticity |
| GO_0045955 | Biological process | negative regulation of calcium ion-dependent exocytosis |
| GO_0030154 | Biological process | cell differentiation |
| GO_1905433 | Biological process | negative regulation of retrograde trans-synaptic signaling by neuropeptide |
| GO_0045956 | Biological process | positive regulation of calcium ion-dependent exocytosis |
| GO_0030100 | Biological process | regulation of endocytosis |
| GO_0007613 | Biological process | memory |
| GO_0006906 | Biological process | vesicle fusion |
| GO_0150044 | Biological process | regulation of postsynaptic dense core vesicle exocytosis |
| GO_0033604 | Biological process | negative regulation of catecholamine secretion |
| GO_1905415 | Biological process | positive regulation of dense core granule exocytosis |
| GO_0150035 | Biological process | regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission |
| GO_0070382 | Cellular component | exocytic vesicle |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0098992 | Cellular component | neuronal dense core vesicle |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_1990742 | Cellular component | microvesicle |
| GO_0030672 | Cellular component | synaptic vesicle membrane |
| GO_0099012 | Cellular component | neuronal dense core vesicle membrane |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0032127 | Cellular component | dense core granule membrane |
| GO_0030425 | Cellular component | dendrite |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0045202 | Cellular component | synapse |
| GO_0097449 | Cellular component | astrocyte projection |
| GO_0030424 | Cellular component | axon |
| GO_0005544 | Molecular function | calcium-dependent phospholipid binding |
| GO_0001786 | Molecular function | phosphatidylserine binding |
| GO_0000149 | Molecular function | SNARE binding |
| GO_0030276 | Molecular function | clathrin binding |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SYT4 |
| Protein name | Synaptotagmin-4 (Synaptotagmin IV) (SytIV) Synaptotagmin 4 |
| Synonyms | KIAA1342 |
| Description | FUNCTION: Synaptotagmin family member which does not bind Ca(2+) (By similarity). Involved in neuronal dense core vesicles (DCVs) mobility through its interaction with KIF1A. Upon increased neuronal activity, phosphorylation by MAPK8/JNK1 destabilizes the interaction with KIF1A and captures DCVs to synapses (By similarity). Plays a role in dendrite formation by melanocytes . . |
| Accessions | Q9H2B2 M0QZF3 M0R2I0 ENST00000255224.8 [Q9H2B2-1] ENST00000590752.5 [Q9H2B2-2] ENST00000593720.1 ENST00000596867.1 |
