PURA report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0050673Biological processepithelial cell proliferation
GO_0006268Biological processDNA unwinding involved in DNA replication
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0046651Biological processlymphocyte proliferation
GO_0006270Biological processDNA replication initiation
GO_0098963Biological processdendritic transport of messenger ribonucleoprotein complex
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0007399Biological processnervous system development
GO_0017148Biological processnegative regulation of translation
GO_0098978Cellular componentglutamatergic synapse
GO_0043025Cellular componentneuronal cell body
GO_0098794Cellular componentpostsynapse
GO_0000781Cellular componentchromosome, telomeric region
GO_0032839Cellular componentdendrite cytoplasm
GO_0005634Cellular componentnucleus
GO_0140297Molecular functionDNA-binding transcription factor binding
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0003697Molecular functionsingle-stranded DNA binding
GO_0000900Molecular functionmRNA regulatory element binding translation repressor activity
GO_0140416Molecular functiontranscription regulator inhibitor activity
GO_0046332Molecular functionSMAD binding
GO_0003691Molecular functiondouble-stranded telomeric DNA binding
GO_0003723Molecular functionRNA binding
GO_0032422Molecular functionpurine-rich negative regulatory element binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePURA
Protein namePURA protein
Purine-rich element binding protein A
Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha)
Purine rich element binding protein A
SynonymsPUR1
DescriptionFUNCTION: This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination.

AccessionsQ00577
ENST00000502351.1
A0A494C0X8
Q2NLC9
A0A494C0H6
Q2NLD4
ENST00000331327.5
ENST00000505703.2
ENST00000651386.1
Q56A79