Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 14 studies | 94% ± 6% | |
oligodendrocyte precursor cell | 13 studies | 84% ± 15% | |
glutamatergic neuron | 12 studies | 74% ± 21% | |
GABAergic neuron | 10 studies | 70% ± 24% | |
astrocyte | 9 studies | 36% ± 24% | |
microglial cell | 8 studies | 37% ± 19% | |
fibroblast | 8 studies | 31% ± 14% | |
neuron | 6 studies | 43% ± 19% | |
interneuron | 6 studies | 62% ± 26% | |
cardiac muscle cell | 6 studies | 64% ± 15% | |
pericyte | 6 studies | 32% ± 14% | |
endothelial cell | 5 studies | 49% ± 17% | |
smooth muscle cell | 4 studies | 26% ± 13% | |
retinal ganglion cell | 4 studies | 65% ± 24% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 79% ± 9% | |
GABAergic interneuron | 3 studies | 78% ± 24% | |
glial cell | 3 studies | 55% ± 19% | |
granule cell | 3 studies | 57% ± 7% | |
GABAergic amacrine cell | 3 studies | 66% ± 14% | |
glycinergic amacrine cell | 3 studies | 59% ± 8% | |
amacrine cell | 3 studies | 77% ± 9% | |
mast cell | 3 studies | 31% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 99% | 92.48 | 2625 / 2642 | 70% | 2.41 | 496 / 705 |
bladder | 90% | 48.57 | 19 / 21 | 1% | 0.05 | 7 / 504 |
heart | 85% | 35.44 | 734 / 861 | 0% | 0 | 0 / 0 |
prostate | 46% | 11.00 | 113 / 245 | 31% | 1.31 | 157 / 502 |
intestine | 59% | 16.14 | 569 / 966 | 1% | 0.02 | 4 / 527 |
ovary | 52% | 14.28 | 93 / 180 | 1% | 0.02 | 5 / 430 |
esophagus | 42% | 10.04 | 606 / 1445 | 5% | 0.07 | 9 / 183 |
skin | 6% | 0.92 | 101 / 1809 | 26% | 1.50 | 123 / 472 |
thymus | 29% | 6.38 | 190 / 653 | 2% | 0.04 | 14 / 605 |
adipose | 29% | 5.59 | 347 / 1204 | 0% | 0 | 0 / 0 |
stomach | 25% | 6.03 | 89 / 359 | 3% | 0.05 | 8 / 286 |
breast | 22% | 3.78 | 103 / 459 | 3% | 0.09 | 35 / 1118 |
uterus | 15% | 3.11 | 26 / 170 | 3% | 0.05 | 15 / 459 |
muscle | 16% | 3.02 | 129 / 803 | 0% | 0 | 0 / 0 |
kidney | 9% | 1.38 | 8 / 89 | 1% | 0.03 | 9 / 901 |
blood vessel | 8% | 1.99 | 110 / 1335 | 0% | 0 | 0 / 0 |
liver | 1% | 0.12 | 2 / 226 | 4% | 0.09 | 17 / 406 |
lung | 3% | 0.51 | 19 / 578 | 1% | 0.03 | 15 / 1155 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.16 | 1 / 45 |
eye | 0% | 0 | 0 / 0 | 1% | 0.01 | 1 / 80 |
pancreas | 1% | 0.07 | 2 / 328 | 1% | 0.01 | 1 / 178 |
adrenal gland | 0% | 0.04 | 1 / 258 | 0% | 0.01 | 1 / 230 |
spleen | 0% | 0.05 | 1 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0.03 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_1905606 | Biological process | regulation of presynapse assembly |
GO_0061003 | Biological process | positive regulation of dendritic spine morphogenesis |
GO_0007165 | Biological process | signal transduction |
GO_0099560 | Biological process | synaptic membrane adhesion |
GO_0030182 | Biological process | neuron differentiation |
GO_0099545 | Biological process | trans-synaptic signaling by trans-synaptic complex |
GO_0010975 | Biological process | regulation of neuron projection development |
GO_0045920 | Biological process | negative regulation of exocytosis |
GO_0051965 | Biological process | positive regulation of synapse assembly |
GO_0097105 | Biological process | presynaptic membrane assembly |
GO_0099175 | Biological process | regulation of postsynapse organization |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0030425 | Cellular component | dendrite |
GO_0009986 | Cellular component | cell surface |
GO_0005737 | Cellular component | cytoplasm |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_0030424 | Cellular component | axon |
GO_0003953 | Molecular function | NAD+ nucleosidase activity |
GO_0019966 | Molecular function | interleukin-1 binding |
GO_0005102 | Molecular function | signaling receptor binding |
GO_0005515 | Molecular function | protein binding |
GO_0061809 | Molecular function | NAD+ nucleotidase, cyclic ADP-ribose generating |
Gene name | IL1RAPL1 |
Protein name | Interleukin-1 receptor accessory protein-like 1 (X-linked interleukin-1 receptor accessory protein-like 1) Interleukin-1 receptor accessory protein-like 1 (IL-1-RAPL-1) (IL-1RAPL-1) (IL1RAPL-1) (EC 3.2.2.6) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2) (X-linked interleukin-1 receptor accessory protein-like 1) Interleukin 1 receptor accessory protein-like 1 |
Synonyms | OPHN4 |
Description | FUNCTION: May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel . May activate the MAP kinase JNK . Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity). . |
Accessions | X5DNQ7 Q9NZN1 Q7Z2K4 A0A346RP49 Q7Z2H0 ENST00000378993.6 [Q9NZN1-1] |