FOXF2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FOXF2 at tissue level.

III. Associated gene sets

GO_0032434Biological processregulation of proteasomal ubiquitin-dependent protein catabolic process
GO_0001837Biological processepithelial to mesenchymal transition
GO_0048596Biological processembryonic camera-type eye morphogenesis
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0009887Biological processanimal organ morphogenesis
GO_0048566Biological processembryonic digestive tract development
GO_0030198Biological processextracellular matrix organization
GO_0048806Biological processgenitalia development
GO_0060021Biological processroof of mouth development
GO_1902914Biological processregulation of protein polyubiquitination
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0042249Biological processestablishment of planar polarity of embryonic epithelium
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0016604Cellular componentnuclear body
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0000785Cellular componentchromatin
GO_0005667Cellular componenttranscription regulator complex
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0001093Molecular functionTFIIB-class transcription factor binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0043565Molecular functionsequence-specific DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0140296Molecular functiongeneral transcription initiation factor binding

IV. Literature review

[source]
Gene nameFOXF2
Protein nameForkhead box protein F2 (Forkhead-related activator 2) (FREAC-2) (Forkhead-related protein FKHL6) (Forkhead-related transcription factor 2)
SynonymsFREAC2
FKHL6
DescriptionFUNCTION: Probable transcription activator for a number of lung-specific genes . Mediates up-regulation of the E3 ligase IRF2BPL and drives ubiquitination and degradation of CTNNB1 . .

AccessionsQ12947
ENST00000645481.2