I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| smooth muscle cell | 5 studies | 22% ± 3% | |
| GABAergic neuron | 3 studies | 26% ± 6% | |
| pericyte | 3 studies | 19% ± 2% | |
| oligodendrocyte | 3 studies | 21% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| smooth muscle cell | 5 studies | 22% ± 3% | |
| GABAergic neuron | 3 studies | 26% ± 6% | |
| pericyte | 3 studies | 19% ± 2% | |
| oligodendrocyte | 3 studies | 21% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 22% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 97% | 4180.25 | 2567 / 2642 | 100% | 33.31 | 703 / 705 |
| prostate | 90% | 2679.90 | 221 / 245 | 94% | 9.15 | 470 / 502 |
| lung | 84% | 1691.05 | 486 / 578 | 66% | 4.12 | 761 / 1155 |
| uterus | 99% | 5905.29 | 168 / 170 | 44% | 10.11 | 201 / 459 |
| bladder | 95% | 5039.10 | 20 / 21 | 45% | 3.05 | 227 / 504 |
| ovary | 91% | 2059.73 | 164 / 180 | 47% | 3.00 | 201 / 430 |
| intestine | 76% | 4247.74 | 738 / 966 | 46% | 2.68 | 241 / 527 |
| esophagus | 68% | 3302.99 | 979 / 1445 | 52% | 3.44 | 95 / 183 |
| stomach | 48% | 1924.50 | 174 / 359 | 58% | 5.62 | 167 / 286 |
| breast | 35% | 478.71 | 162 / 459 | 70% | 3.61 | 788 / 1118 |
| blood vessel | 100% | 12679.82 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| pancreas | 0% | 0 | 0 / 328 | 88% | 6.77 | 156 / 178 |
| kidney | 33% | 495.12 | 29 / 89 | 53% | 3.52 | 482 / 901 |
| adrenal gland | 5% | 55.09 | 12 / 258 | 77% | 7.72 | 176 / 230 |
| skin | 10% | 120.77 | 181 / 1809 | 64% | 5.75 | 303 / 472 |
| thymus | 29% | 369.46 | 187 / 653 | 44% | 1.96 | 266 / 605 |
| heart | 72% | 1567.86 | 623 / 861 | 0% | 0 | 0 / 0 |
| spleen | 52% | 656.85 | 126 / 241 | 0% | 0 | 0 / 0 |
| adipose | 46% | 854.80 | 549 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 35% | 1.51 | 28 / 80 |
| liver | 2% | 18.23 | 4 / 226 | 20% | 0.76 | 80 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 16% | 0.65 | 7 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 14% | 0.63 | 4 / 29 |
| muscle | 2% | 35.02 | 19 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0.87 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0030178 | Biological process | negative regulation of Wnt signaling pathway |
| GO_0001837 | Biological process | epithelial to mesenchymal transition |
| GO_0010719 | Biological process | negative regulation of epithelial to mesenchymal transition |
| GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
| GO_0060070 | Biological process | canonical Wnt signaling pathway |
| GO_0030308 | Biological process | negative regulation of cell growth |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0070097 | Molecular function | delta-catenin binding |
| GO_0005080 | Molecular function | protein kinase C binding |
| GO_0051018 | Molecular function | protein kinase A binding |
| GO_0042802 | Molecular function | identical protein binding |
| Gene name | DACT3 |
| Protein name | Dishevelled binding antagonist of beta catenin 3 (Thymus expressed gene 3-like, isoform CRA_c) Dishevelled binding antagonist of beta catenin 3 (Thymus expressed gene 3-like, isoform CRA_b) Dapper homolog 3 (Antagonist of beta-catenin Dapper homolog 3) (Arginine-rich region 1 protein) (Dapper antagonist of catenin 3) |
| Synonyms | RRR1 MGC15476 hCG_1656651 |
| Description | FUNCTION: May be involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins. . |
| Accessions | A0A0C4DFP1 Q96B18 G5E9H6 ENST00000391916.7 ENST00000410105.2 ENST00000300875.4 |
