SP6 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SP6 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SP6 at tissue level.

III. Associated gene sets

GO_0042481Biological processregulation of odontogenesis
GO_0001837Biological processepithelial to mesenchymal transition
GO_0042476Biological processodontogenesis
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005829Cellular componentcytosol
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameSP6
Protein nameTranscription factor Sp6 (Krueppel-like factor 14)
SynonymsKLF14
DescriptionFUNCTION: Promotes cell proliferation (By similarity). Plays a role in tooth germ growth (By similarity). Plays a role in the control of enamel mineralization. Binds the AMBN promoter . .

AccessionsQ3SY56
ENST00000342234.3
ENST00000536300.2