mesenchymal to epithelial transition

I. Involved cell types

Genes
Cell types
No. of supported studies
Group 1
WNT4
pancreatic A celltype B pancreatic cell
3 studies
Group 2
WT1
mesothelial cellpodocyte
14 studies
Group 3
PAX2GATA3
renal principal cell
5 studies
Group 4
CITED1
epithelial cellglial cellneuron
3 studies
Group 5
BASP1PELO
epithelial cell
6 studies

II. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1WNT4-FZD7+LRP5WNT4_HUMAN - Ligand-ReceptorSignaling by WNT
2WNT4-FZD7+LRP6WNT4_HUMAN - Ligand-ReceptorSignaling by WNT

III. Literature review

[source]
Namemesenchymal to epithelial transition
IDGO_0060231
collection_id

Biological process

Exact synonym

epithelial cell differentiation from mesenchymal cell, mesenchymal-epithelial transition

Description

A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.

External URL
Genes
TCF15CITED1GATA3BASP1FZD7WNT4PELOPAX2WT1