PTH report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PTH at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PTH at tissue level.

III. Associated gene sets

GO_0055062Biological processphosphate ion homeostasis
GO_0006366Biological processtranscription by RNA polymerase II
GO_0071107Biological processresponse to parathyroid hormone
GO_0010468Biological processregulation of gene expression
GO_0046326Biological processpositive regulation of glucose import
GO_0010629Biological processnegative regulation of gene expression
GO_0008628Biological processhormone-mediated apoptotic signaling pathway
GO_0010628Biological processpositive regulation of gene expression
GO_0009967Biological processpositive regulation of signal transduction
GO_0010288Biological processresponse to lead ion
GO_0060732Biological processpositive regulation of inositol phosphate biosynthetic process
GO_0006874Biological processintracellular calcium ion homeostasis
GO_0045471Biological processresponse to ethanol
GO_0090290Biological processpositive regulation of osteoclast proliferation
GO_0007267Biological processcell-cell signaling
GO_0048873Biological processhomeostasis of number of cells within a tissue
GO_0032331Biological processnegative regulation of chondrocyte differentiation
GO_0045725Biological processpositive regulation of glycogen biosynthetic process
GO_0046058Biological processcAMP metabolic process
GO_0046686Biological processresponse to cadmium ion
GO_0071774Biological processresponse to fibroblast growth factor
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0071864Biological processpositive regulation of cell proliferation in bone marrow
GO_0009059Biological processmacromolecule biosynthetic process
GO_0030282Biological processbone mineralization
GO_1900158Biological processnegative regulation of bone mineralization involved in bone maturation
GO_0045453Biological processbone resorption
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0001501Biological processskeletal system development
GO_0007266Biological processRho protein signal transduction
GO_0010960Biological processmagnesium ion homeostasis
GO_0009410Biological processresponse to xenobiotic stimulus
GO_0030501Biological processpositive regulation of bone mineralization
GO_0033280Biological processresponse to vitamin D
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0071866Biological processnegative regulation of apoptotic process in bone marrow cell
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0051428Molecular functionpeptide hormone receptor binding
GO_0048018Molecular functionreceptor ligand activity
GO_0031857Molecular functiontype 1 parathyroid hormone receptor binding
GO_0005179Molecular functionhormone activity
GO_0031856Molecular functionparathyroid hormone receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePTH
Protein nameParathyroid hormone (PTH) (Parathormone) (Parathyrin)
Synonyms
DescriptionFUNCTION: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. .

AccessionsP01270
ENST00000282091.6
ENST00000529816.1