Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| classical monocyte | 12 studies | 28% ± 8% | |
| non-classical monocyte | 11 studies | 32% ± 12% | |
| macrophage | 10 studies | 26% ± 13% | |
| conventional dendritic cell | 8 studies | 27% ± 13% | |
| plasmacytoid dendritic cell | 7 studies | 22% ± 4% | |
| dendritic cell | 4 studies | 26% ± 6% | |
| myeloid cell | 4 studies | 19% ± 4% | |
| monocyte | 4 studies | 25% ± 7% | |
| alveolar macrophage | 3 studies | 37% ± 18% |
Insufficient scRNA-seq data for expression of TNFSF13 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 2130.19 | 180 / 180 | 98% | 14.22 | 421 / 430 |
| kidney | 100% | 4403.12 | 89 / 89 | 98% | 31.61 | 881 / 901 |
| thymus | 100% | 2514.90 | 653 / 653 | 97% | 22.05 | 588 / 605 |
| prostate | 100% | 2172.17 | 245 / 245 | 97% | 13.43 | 485 / 502 |
| intestine | 100% | 2388.39 | 964 / 966 | 97% | 16.64 | 510 / 527 |
| breast | 100% | 1854.24 | 459 / 459 | 97% | 14.90 | 1079 / 1118 |
| stomach | 100% | 2770.56 | 359 / 359 | 97% | 14.96 | 276 / 286 |
| brain | 99% | 2076.68 | 2603 / 2642 | 97% | 8.33 | 683 / 705 |
| lung | 100% | 5397.15 | 578 / 578 | 95% | 13.73 | 1095 / 1155 |
| pancreas | 100% | 1489.70 | 328 / 328 | 94% | 17.25 | 167 / 178 |
| bladder | 100% | 1282.43 | 21 / 21 | 87% | 9.35 | 440 / 504 |
| uterus | 100% | 1420.38 | 170 / 170 | 80% | 6.90 | 365 / 459 |
| esophagus | 98% | 1354.64 | 1412 / 1445 | 70% | 6.92 | 128 / 183 |
| skin | 78% | 705.49 | 1409 / 1809 | 87% | 9.41 | 412 / 472 |
| adrenal gland | 100% | 2418.76 | 258 / 258 | 52% | 3.28 | 120 / 230 |
| liver | 94% | 750.16 | 213 / 226 | 28% | 2.02 | 113 / 406 |
| spleen | 100% | 2947.02 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 100% | 2109.95 | 1200 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1993.94 | 1329 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 3318.26 | 920 / 929 | 0% | 0 | 0 / 0 |
| heart | 83% | 833.72 | 718 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 8.84 | 24 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 78% | 6.06 | 35 / 45 |
| eye | 0% | 0 | 0 / 0 | 78% | 4.60 | 62 / 80 |
| muscle | 20% | 108.51 | 163 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007165 | Biological process | signal transduction |
| GO_0006955 | Biological process | immune response |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0048298 | Biological process | positive regulation of isotype switching to IgA isotypes |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005576 | Cellular component | extracellular region |
| GO_0016020 | Cellular component | membrane |
| GO_0005164 | Molecular function | tumor necrosis factor receptor binding |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0005125 | Molecular function | cytokine activity |
| GO_0048018 | Molecular function | receptor ligand activity |
| Gene name | TNFSF13 |
| Protein name | TNF superfamily member 13 (Tumor necrosis factor (Ligand) superfamily member 13 transcript variant delta) TNFSF13 protein HCG2045906, isoform CRA_d (TNFSF13 protein) (Tumor necrosis factor (Ligand) superfamily, member 13) Tumor necrosis factor ligand superfamily member 13 (A proliferation-inducing ligand) (APRIL) (TNF- and APOL-related leukocyte expressed ligand 2) (TALL-2) (TNF-related death ligand 1) (TRDL-1) (CD antigen CD256) Tumor necrosis factor ligand superfamily member 13 epsilon TNF superfamily member 13 |
| Synonyms | UNQ383/PRO715 ZTNF2 TALL2 APRIL hCG_2045906 |
| Description | FUNCTION: Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. . |
| Accessions | ENST00000438470.5 ENST00000483039.5 ENST00000625791.2 [O75888-4] ENST00000396545.4 [O75888-3] ENST00000436057.5 C9JF68 Q6FGR7 K7EJ28 C9JFN2 ENST00000338784.9 [O75888-1] O75888 Q6FGN4 ENST00000396542.5 [O75888-5] ENST00000349228.8 [O75888-2] ENST00000380535.8 Q2QBA2 A5Y848 |
