CCL26 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CCL26 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CCL26 at tissue level.

III. Associated gene sets

GO_0030838Biological processpositive regulation of actin filament polymerization
GO_0006954Biological processinflammatory response
GO_0043547Biological processpositive regulation of GTPase activity
GO_0050921Biological processpositive regulation of chemotaxis
GO_0007165Biological processsignal transduction
GO_0006935Biological processchemotaxis
GO_0007267Biological processcell-cell signaling
GO_0070098Biological processchemokine-mediated signaling pathway
GO_0001938Biological processpositive regulation of endothelial cell proliferation
GO_0030335Biological processpositive regulation of cell migration
GO_0048245Biological processeosinophil chemotaxis
GO_0061844Biological processantimicrobial humoral immune response mediated by antimicrobial peptide
GO_0002548Biological processmonocyte chemotaxis
GO_0010818Biological processT cell chemotaxis
GO_0005615Cellular componentextracellular space
GO_0031737Molecular functionCX3C chemokine receptor binding
GO_0008009Molecular functionchemokine activity
GO_0048018Molecular functionreceptor ligand activity
GO_0048020Molecular functionCCR chemokine receptor binding
GO_0031728Molecular functionCCR3 chemokine receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCCL26
Protein nameC-C motif chemokine 26 (CC chemokine IMAC) (Eotaxin-3) (Macrophage inflammatory protein 4-alpha) (MIP-4-alpha) (Small-inducible cytokine A26) (Thymic stroma chemokine-1) (TSC-1)
SynonymsUNQ216/PRO242
SCYA26
DescriptionFUNCTION: Chemoattractant for eosinophils and basophils . Acts as a ligand for C-C chemokine receptor CCR3 which triggers Ca(2+) mobilization in eosinophils . Also acts as a ligand for CX3C chemokine receptor CX3CR1, inducing cell chemotaxis . .

AccessionsENST00000394905.2
ENST00000005180.9
Q9Y258