I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| fibroblast | 5 studies | 38% ± 15% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 5 studies | 38% ± 15% |
Insufficient scRNA-seq data for expression of CCL11 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| stomach | 91% | 778.63 | 325 / 359 | 87% | 30.72 | 250 / 286 |
| intestine | 95% | 1301.28 | 922 / 966 | 79% | 18.25 | 414 / 527 |
| esophagus | 71% | 268.31 | 1030 / 1445 | 81% | 16.44 | 149 / 183 |
| lung | 52% | 357.65 | 298 / 578 | 72% | 13.44 | 834 / 1155 |
| bladder | 52% | 447.43 | 11 / 21 | 71% | 18.65 | 357 / 504 |
| pancreas | 27% | 65.91 | 89 / 328 | 79% | 11.30 | 141 / 178 |
| uterus | 49% | 156.27 | 83 / 170 | 47% | 8.68 | 214 / 459 |
| kidney | 54% | 177.26 | 48 / 89 | 10% | 0.76 | 87 / 901 |
| ovary | 7% | 8.97 | 13 / 180 | 56% | 10.35 | 242 / 430 |
| prostate | 38% | 105.15 | 92 / 245 | 24% | 1.22 | 120 / 502 |
| heart | 60% | 238.95 | 513 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 58% | 6.95 | 26 / 45 |
| breast | 1% | 7.18 | 3 / 459 | 51% | 4.47 | 566 / 1118 |
| adipose | 23% | 70.26 | 274 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 21% | 1.84 | 6 / 29 |
| adrenal gland | 7% | 12.65 | 19 / 258 | 10% | 1.43 | 23 / 230 |
| skin | 1% | 1.91 | 22 / 1809 | 15% | 1.09 | 70 / 472 |
| liver | 4% | 7.12 | 9 / 226 | 10% | 0.65 | 42 / 406 |
| spleen | 6% | 8.09 | 15 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 5% | 11.62 | 72 / 1335 | 0% | 0 | 0 / 0 |
| thymus | 0% | 0.13 | 1 / 653 | 2% | 0.27 | 15 / 605 |
| brain | 0% | 0 | 0 / 2642 | 1% | 0.27 | 5 / 705 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0002544 | Biological process | chronic inflammatory response |
| GO_0030838 | Biological process | positive regulation of actin filament polymerization |
| GO_0060763 | Biological process | mammary duct terminal end bud growth |
| GO_0006954 | Biological process | inflammatory response |
| GO_0043547 | Biological process | positive regulation of GTPase activity |
| GO_0060444 | Biological process | branching involved in mammary gland duct morphogenesis |
| GO_0007611 | Biological process | learning or memory |
| GO_0045766 | Biological process | positive regulation of angiogenesis |
| GO_0009314 | Biological process | response to radiation |
| GO_0007165 | Biological process | signal transduction |
| GO_0009615 | Biological process | response to virus |
| GO_0006935 | Biological process | chemotaxis |
| GO_0007155 | Biological process | cell adhesion |
| GO_0007010 | Biological process | cytoskeleton organization |
| GO_0006874 | Biological process | intracellular calcium ion homeostasis |
| GO_0070371 | Biological process | ERK1 and ERK2 cascade |
| GO_0070098 | Biological process | chemokine-mediated signaling pathway |
| GO_0001938 | Biological process | positive regulation of endothelial cell proliferation |
| GO_0030335 | Biological process | positive regulation of cell migration |
| GO_0007015 | Biological process | actin filament organization |
| GO_0070670 | Biological process | response to interleukin-4 |
| GO_0048245 | Biological process | eosinophil chemotaxis |
| GO_0061844 | Biological process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| GO_0008360 | Biological process | regulation of cell shape |
| GO_0006468 | Biological process | protein phosphorylation |
| GO_0035962 | Biological process | response to interleukin-13 |
| GO_0002551 | Biological process | mast cell chemotaxis |
| GO_0050768 | Biological process | negative regulation of neurogenesis |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0008009 | Molecular function | chemokine activity |
| GO_0048018 | Molecular function | receptor ligand activity |
| GO_0048020 | Molecular function | CCR chemokine receptor binding |
| GO_0031728 | Molecular function | CCR3 chemokine receptor binding |
| GO_0046983 | Molecular function | protein dimerization activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CCL11 |
| Protein name | Eotaxin (C-C motif chemokine 11) (Eosinophil chemotactic protein) (Small-inducible cytokine A11) C-C motif chemokine |
| Synonyms | hCG_29299 SCYA11 |
| Description | FUNCTION: In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions . Binds to CCR3 . . |
| Accessions | Q6I9T4 P51671 ENST00000305869.4 |
