Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 34 studies | 38% ± 18% | |
fibroblast | 20 studies | 41% ± 15% | |
myeloid cell | 11 studies | 32% ± 13% | |
alveolar macrophage | 8 studies | 62% ± 21% | |
connective tissue cell | 6 studies | 28% ± 8% | |
oligodendrocyte precursor cell | 6 studies | 30% ± 7% | |
melanocyte | 6 studies | 66% ± 20% | |
pericyte | 6 studies | 26% ± 6% | |
microglial cell | 4 studies | 24% ± 8% | |
monocyte | 4 studies | 37% ± 18% | |
retinal pigment epithelial cell | 4 studies | 55% ± 26% | |
adventitial cell | 4 studies | 45% ± 13% | |
smooth muscle cell | 4 studies | 19% ± 4% | |
keratinocyte | 4 studies | 40% ± 15% | |
kidney loop of Henle epithelial cell | 3 studies | 24% ± 4% | |
tissue-resident macrophage | 3 studies | 37% ± 13% | |
basal cell | 3 studies | 19% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
skin | 100% | 35124.28 | 1809 / 1809 | 98% | 1052.82 | 462 / 472 |
breast | 98% | 18236.28 | 449 / 459 | 84% | 153.35 | 942 / 1118 |
lung | 89% | 10825.57 | 515 / 578 | 83% | 424.74 | 964 / 1155 |
uterus | 100% | 18675.96 | 170 / 170 | 65% | 233.55 | 298 / 459 |
esophagus | 93% | 8464.76 | 1348 / 1445 | 58% | 274.22 | 107 / 183 |
bladder | 86% | 8813.00 | 18 / 21 | 52% | 149.09 | 263 / 504 |
thymus | 91% | 7406.41 | 591 / 653 | 40% | 68.11 | 242 / 605 |
intestine | 88% | 9083.61 | 847 / 966 | 31% | 41.94 | 164 / 527 |
ovary | 74% | 5152.21 | 134 / 180 | 43% | 53.30 | 186 / 430 |
eye | 0% | 0 | 0 / 0 | 100% | 751.10 | 80 / 80 |
blood vessel | 100% | 17685.18 | 1332 / 1335 | 0% | 0 | 0 / 0 |
adipose | 99% | 20117.19 | 1192 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 90% | 287.01 | 26 / 29 |
kidney | 20% | 1165.35 | 18 / 89 | 69% | 247.48 | 625 / 901 |
heart | 90% | 10072.38 | 771 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 87% | 368.86 | 39 / 45 |
stomach | 37% | 3831.96 | 134 / 359 | 45% | 60.41 | 128 / 286 |
pancreas | 5% | 281.55 | 18 / 328 | 74% | 121.14 | 132 / 178 |
prostate | 53% | 3030.61 | 130 / 245 | 21% | 20.18 | 107 / 502 |
brain | 14% | 719.47 | 360 / 2642 | 25% | 35.46 | 177 / 705 |
adrenal gland | 17% | 765.22 | 44 / 258 | 12% | 13.17 | 28 / 230 |
spleen | 18% | 750.63 | 43 / 241 | 0% | 0 | 0 / 0 |
liver | 2% | 84.44 | 5 / 226 | 11% | 18.79 | 44 / 406 |
muscle | 9% | 381.11 | 71 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 2% | 165.83 | 17 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0050918 | Biological process | positive chemotaxis |
GO_0007165 | Biological process | signal transduction |
GO_0050868 | Biological process | negative regulation of T cell activation |
GO_0007155 | Biological process | cell adhesion |
GO_0001934 | Biological process | positive regulation of protein phosphorylation |
GO_0007267 | Biological process | cell-cell signaling |
GO_0045765 | Biological process | regulation of angiogenesis |
GO_0030335 | Biological process | positive regulation of cell migration |
GO_0042130 | Biological process | negative regulation of T cell proliferation |
GO_0034103 | Biological process | regulation of tissue remodeling |
GO_0001818 | Biological process | negative regulation of cytokine production |
GO_2000134 | Biological process | negative regulation of G1/S transition of mitotic cell cycle |
GO_0031954 | Biological process | positive regulation of protein autophosphorylation |
GO_0032720 | Biological process | negative regulation of tumor necrosis factor production |
GO_0070374 | Biological process | positive regulation of ERK1 and ERK2 cascade |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0031901 | Cellular component | early endosome membrane |
GO_0033162 | Cellular component | melanosome membrane |
GO_0008201 | Molecular function | heparin binding |
GO_0048018 | Molecular function | receptor ligand activity |
GO_0045545 | Molecular function | syndecan binding |
GO_0005178 | Molecular function | integrin binding |
GO_0042056 | Molecular function | chemoattractant activity |
GO_0005515 | Molecular function | protein binding |
Gene name | GPNMB |
Protein name | Glycoprotein nmb Glycoprotein nmb-like protein GPNMB protein (Glycoprotein (Transmembrane) nmb) (Glycoprotein nmb) Transmembrane glycoprotein NMB (Hematopoietic growth factor inducible neurokinin-1 type) |
Synonyms | UNQ1725/PRO9925 hCG_37976 HGFIN NMB |
Description | FUNCTION: Could be a melanogenic enzyme. . |
Accessions | Q96F58 ENST00000409458.3 ENST00000647578.1 Q14956 Q8IXJ5 ENST00000258733.9 [Q14956-2] A0A3B3ISS6 ENST00000381990.6 [Q14956-1] |